| Product Number |
ARP43048_T100 |
| Product Page |
www.avivasysbio.com/hip2-antibody-n-terminal-region-arp43048-t100.html |
| Name |
HIP2 Antibody - N-terminal region (ARP43048_T100) |
| Protein Size (# AA) |
200 amino acids |
| Molecular Weight |
22kDa |
| NCBI Gene Id |
3093 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Ubiquitin-conjugating enzyme E2K |
| Alias Symbols |
LIG, HIP2, HYPG, UBC1, E2-25K |
| Peptide Sequence |
Synthetic peptide located within the following region: MANIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lee,S.J., (2001) FEBS Lett. 503 (1), 61-64 |
| Description of Target |
HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis. |
| Protein Interactions |
DDI1; DTX3; MIPOL1; TRIM39; ANAPC11; RNF138; SIAH1; RNF5; REL; FZR1; UBC; UBA1; MARCH7; AMFR; TP53; MDM2; BAG3; PRRG4; IQCB1; HTT; CDC6; WDR1; TYMS; TXN; TXNDC17; WDR61; ITCH; NEDD4L; WWP2; NXF1; NUB1; PIAS4; CASP12; SUMO1; SUMO2; DIABLO; UBE2I; CCNB1; BR |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-UBE2K (ARP43048_T100) antibody |
| Blocking Peptide |
For anti-UBE2K (ARP43048_T100) antibody is Catalog # AAP43048 (Previous Catalog # AAPP25026) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human HIP2 |
| Uniprot ID |
P61086 |
| Protein Name |
Ubiquitin-conjugating enzyme E2 K |
| Protein Accession # |
NP_005330 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_005339 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
UBE2K |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-HIP2 Antibody Titration: 5.0ug/ml
Positive Control: Jurkat cell lysate |
|
