UBE2L3 Antibody - C-terminal region (ARP43026_P050)

Data Sheet
 
Product Number ARP43026_P050
Product Page www.avivasysbio.com/ube2l3-antibody-c-terminal-region-arp43026-p050.html
Name UBE2L3 Antibody - C-terminal region (ARP43026_P050)
Protein Size (# AA) 154 amino acids
Molecular Weight 17kDa
NCBI Gene Id 7332
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Ubiquitin-conjugating enzyme E2L 3
Alias Symbols E2-F1, L-UBC, UBCH7, UbcM4
Peptide Sequence Synthetic peptide located within the following region: IQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Collins,J.E., Genome Biol. 5 (10), R84 (2004)
Description of Target UBE2L3(ubiquitin-conjugating enzyme E2L 3) Antibody The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Protein Interactions UBC; TRAF6; NEDD4; ITCH; MUL1; SMURF2; SMURF1; WWP2; WWP1; ARIH2; RNF144A; UBA1; PARK2; RNF144B; HACE1; ARIH1; UBE3A; UBE2L3; UBA6; UBR5; CACNA1B; MAP1LC3B; BAG3; HSPA4; AICDA; CCNB1IP1; FN1; RBX1; LIG4; ZPR1; USP9X; SF1; VDAC2; UCHL3; UBE2V2; UBE2D2; UBE
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-UBE2L3 (ARP43026_P050) antibody
Blocking Peptide For anti-UBE2L3 (ARP43026_P050) antibody is Catalog # AAP43026 (Previous Catalog # AAPP11233)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human UBE2L3
Uniprot ID P68036
Protein Name Ubiquitin-conjugating enzyme E2 L3
Sample Type Confirmation

There is BioGPS gene expression data showing that UBE2L3 is expressed in Jurkat

Protein Accession # NP_003338
Purification Affinity Purified
Nucleotide Accession # NM_003347
Tested Species Reactivity Human
Gene Symbol UBE2L3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Image 1
Human Prostate
Immunohistochemistry with Human Prostate lysate tissue at an antibody concentration of 5.0ug/ml using anti-UBE2L3 antibody (ARP43026_P050)
Image 2
Human Jurkat
WB Suggested Anti-UBE2L3 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysateThere is BioGPS gene expression data showing that UBE2L3 is expressed in Jurkat
 

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