| Product Number |
ARP42226_T100 |
| Product Page |
www.avivasysbio.com/gem-antibody-c-terminal-region-arp42226-t100.html |
| Name |
GEM Antibody - C-terminal region (ARP42226_T100) |
| Protein Size (# AA) |
296 amino acids |
| Molecular Weight |
33kDa |
| NCBI Gene Id |
2669 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
GTP binding protein overexpressed in skeletal muscle |
| Alias Symbols |
KIR |
| Peptide Sequence |
Synthetic peptide located within the following region: ETSAAVQHNVKELFEGIVRQVRLRRDSKEKNERRLAYQKRKESMPRKARRFW |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Sano,A., (2005) Trends Cell Biol. 15 (12), 640-643 |
| Description of Target |
GEM belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction.The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. |
| Protein Interactions |
NOTCH2NL; KRTAP10-3; KRTAP10-7; INO80E; CCDC67; KLC3; KRT40; SSX2IP; LZTS2; COG8; CCDC102B; TRIM54; KCTD9; TFIP11; IKZF3; RUNDC3A; AHCYL1; PNMA1; BLZF1; TRAF1; TCF4; TRIM27; KRT31; GOLGA2; TRIM23; CLDN15; CLEC4G; YBEY; NDUFAF3; RNF7; VTN; SDHB; NDUFS8; CT |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Enhanced Validation |
| Relative Expression (Western Blot) |
 |
|
| Datasheets/Manuals |
Printable datasheet for anti-GEM (ARP42226_T100) antibody |
| Blocking Peptide |
For anti-GEM (ARP42226_T100) antibody is Catalog # AAP42226 (Previous Catalog # AAPP24649) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GEM |
| Uniprot ID |
P55040 |
| Protein Name |
GTP-binding protein GEM |
| Protein Accession # |
NP_005252 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_005261 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
GEM |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Stomach Tumor
 | Host: Rabbit
Target Name: GEM
Sample Tissue: Human Stomach Tumor
Antibody Dilution: 1.0ug/ml |
|
| Image 2 | Human skin
 | Rabbit Anti-GEM Antibody
Catalog Number: ARP42226
Paraffin Embedded Tissue: Human Skin
Cellular Data: Squamous epithelial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 3 | Human Kidney
 | Rabbit Anti-GEM Antibody
Catalog Number: ARP42226
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
