| Product Number |
ARP42028_P050 |
| Product Page |
www.avivasysbio.com/krt8-antibody-arp42028-p050.html |
| Name |
KRT8 Antibody (ARP42028_P050) |
| Protein Size (# AA) |
483 amino acids |
| Molecular Weight |
53kDa |
| NCBI Gene Id |
3856 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Keratin 8 |
| Alias Symbols |
K8, KO, CK8, CK-8, CYK8, K2C8, CARD2 |
| Peptide Sequence |
Synthetic peptide located within the following region: MSIRVTQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Oh,J.H., (2005) Mamm. Genome 16 (12), 942-954 |
| Description of Target |
KRT8 together with KRT19, help to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
| Protein Interactions |
KRT31; KRT15; KRT13; KRT40; TFIP11; KRT38; UBC; MDM2; ASB12; EED; GRB2; FBXO25; PAN2; IQCB1; IKBKG; VCAM1; NOS2; KRT18; KPNA2; ITGA4; FN1; ATF2; CDH1; STAM2; CRK; UBASH3B; APEX1; RCHY1; SQSTM1; SUMO1; SUMO2; SUMO3; MAPK8; QRSL1; YWHAQ; TJP1; TADA2A; USP32 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-KRT8 (ARP42028_P050) antibody |
| Blocking Peptide |
For anti-KRT8 (ARP42028_P050) antibody is Catalog # AAP42028 (Previous Catalog # AAPP24509) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human KRT8 |
| Uniprot ID |
P05787 |
| Protein Name |
Keratin, type II cytoskeletal 8 |
| Protein Accession # |
NP_002264 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_002273 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
KRT8 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 92%; Rat: 92%; Yeast: 92% |
| Image 1 | Human Lung
 | Rabbit Anti-KRT8 Antibody
Catalog Number: ARP42028
Paraffin Embedded Tissue: Human alveolar cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 2 | Human Jurkat
 | WB Suggested Anti-KRT8 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate |
|
| Image 3 | Human Intestine
 | Small intestine |
|
| Image 4 | Human
 |
Sample Type: Human Triple Negative Breast Cancer XenograftsPrimary Dilution: 1:100Secondary (Anti-Rabbit 594) Dilution: 1:200 |
|
| Image 5 | Human Kidney
 | Rabbit Anti-KRT8 Antibody
Catalog Number: ARP42028
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 6 | Human Liver Tissue
 | KRT8 Antibody (ARP42028_P050)
Catalog Number: ARP42028_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm and membrane of hepatocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1/600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
