| Product Number |
ARP41743_T100 |
| Product Page |
www.avivasysbio.com/stk11-antibody-n-terminal-region-arp41743-t100.html |
| Name |
STK11 Antibody - N-terminal region (ARP41743_T100) |
| Protein Size (# AA) |
433 amino acids |
| Molecular Weight |
48kDa |
| NCBI Gene Id |
6794 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Serine/threonine kinase 11 |
| Alias Symbols |
PJS, LKB1, hLKB1 |
| Peptide Sequence |
Synthetic peptide located within the following region: TLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Xie,Z., (2006) J. Biol. Chem. 281 (10), 6366-6375 |
| Description of Target |
STK11is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in its gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
| Protein Interactions |
SPDEF; SIRT1; PRKAA1; ETV4; CDC37; HSP90AA1; TP63; Eif2b1; Ap2m1; SNRK; APP; TNIP2; SIK1; STRADA; STUB1; UBE2D2; MARK2; GSK3B; STRADB; CAB39; KIF23; USP11; SMARCC1; SMARCA4; LIMS1; HSPA1A; FKBP5; RPAP3; MARK4; UBC; CAB39L; WDR48; RPS6KB1; MOB4; MARK1; RPS |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-STK11 (ARP41743_T100) antibody |
| Blocking Peptide |
For anti-STK11 (ARP41743_T100) antibody is Catalog # AAP41743 (Previous Catalog # AAPP24386) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human STK11 |
| Uniprot ID |
Q15831 |
| Protein Name |
Serine/threonine-protein kinase STK11 |
| Sample Type Confirmation |
STK11 is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_000446 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_000455 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
STK11 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human Skeletal muscle
 | Rabbit Anti-STK11 Antibody
Catalog Number: ARP41743
Paraffin Embedded Tissue: Human Muscle
Cellular Data: Skeletal muscle cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 2 | Human 293T
 | Host: Rabbit
Target Name: STK11
Sample Tissue: Human 293T
Antibody Dilution: 1.0ug/ml |
|
