Product Number |
ARP41439_T100 |
Product Page |
www.avivasysbio.com/slc13a3-antibody-middle-region-arp41439-t100.html |
Name |
SLC13A3 Antibody - middle region (ARP41439_T100) |
Protein Size (# AA) |
555 amino acids |
Molecular Weight |
61kDa |
NCBI Gene Id |
64849 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
Alias Symbols |
NADC3, SDCT2, ARLIAK |
Peptide Sequence |
Synthetic peptide located within the following region: GLSFRGWRKNKSEIRTNAEDRARAVIREEYQNLGPIKFAEQAVFILFCMF |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Bai,X., (2006) J. Cell. Physiol. 206 (3), 821-830 |
Description of Target |
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. SLC13A3 represents the high-affinity form.Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet. |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SLC13A3 (ARP41439_T100) antibody |
Blocking Peptide |
For anti-SLC13A3 (ARP41439_T100) antibody is Catalog # AAP41439 (Previous Catalog # AAPP24176) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human SLC13A3 |
Uniprot ID |
Q8WWT9 |
Protein Name |
Solute carrier family 13 member 3 |
Protein Accession # |
NP_001011554 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001011554 |
Tested Species Reactivity |
Human |
Gene Symbol |
SLC13A3 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 85%; Rabbit: 93%; Rat: 92%; Zebrafish: 77% |
Image 1 | HepG2, 293T
| Host: Rabbit Target: SLC13A3 Positive control (+): HepG2 (HG) Negative control (-): 293T (2T) Antibody concentration: 2.5ug/ml |
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Image 2 | Human Jurkat
| WB Suggested Anti-SLC13A3 Antibody Titration: 2.5ug/ml Positive Control: Jurkat cell lysate |
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Image 3 | Human Kidney
| Rabbit Anti-SLC13A3 Antibody Catalog Number: ARP41439 Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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