| Product Number |
ARP41367_T100 |
| Product Page |
www.avivasysbio.com/ass-antibody-c-terminal-region-arp41367-t100.html |
| Name |
ASS Antibody - C-terminal region (ARP41367_T100) |
| Protein Size (# AA) |
412 amino acids |
| Molecular Weight |
47 kDa |
| NCBI Gene Id |
445 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Argininosuccinate synthase 1 |
| Alias Symbols |
ASS, CTLN1 |
| Peptide Sequence |
Synthetic peptide located within the following region: SVLKGQVYILGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Hao,G., (2004) J. Biol. Chem. 279 (35), 36192-36200 |
| Description of Target |
ASS catalyzes the penultimate step of the arginine biosynthetic pathway.The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene. |
| Protein Interactions |
ASS1; UBC; ASB18; ASB9; NHLRC2; ATG3; CNDP2; NANS; TNFAIP8; NAMPT; DPP3; RPL23; CTSA; PEPD; MVD; HSPA9; GSS; GBP2; EIF4E; DLD; CAPN1; FBXO6; LATS1; MT2A; MLH1; JAK2; PTPN1; GIT2; SPR; APP; USP4; TERF2; TERF1; SUMO2; AI837181; MYC; ASCC2; AKTIP; ARAF; ELN; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Enhanced Validation |
| Relative Expression (Western Blot) |
 |
|
| Datasheets/Manuals |
Printable datasheet for anti-ASS1 (ARP41367_T100) antibody |
| Blocking Peptide |
For anti-ASS1 (ARP41367_T100) antibody is Catalog # AAP41367 (Previous Catalog # AAPP24106) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human ASS |
| Uniprot ID |
P00966 |
| Protein Name |
Argininosuccinate synthase |
| Publications |
Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 |
| Protein Accession # |
NP_446464 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_054012 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ASS1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Goat: 92%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93% |
| Image 1 | Human HepG2
 | WB Suggested Anti-ASS Antibody Titration: 2.5ug/ml
Positive Control: HepG2 cell lysate |
|
| Image 2 | Human Kidney
 | Rabbit Anti-ASS Antibody
Catalog Number: ARP41367
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 3 | Western Blot
 | 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. |
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