| Product Number |
ARP41348_P050 |
| Product Page |
www.avivasysbio.com/msh6-antibody-n-terminal-region-arp41348-p050.html |
| Name |
MSH6 Antibody - N-terminal region (ARP41348_P050) |
| Protein Size (# AA) |
1360 amino acids |
| Molecular Weight |
153kDa |
| NCBI Gene Id |
2956 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
MutS homolog 6 (E. coli) |
| Alias Symbols |
GTBP, HSAP, p160, GTMBP, HNPCC5, MMRCS3 |
| Peptide Sequence |
Synthetic peptide located within the following region: ISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Magnusson,S., (er) Fam. Cancer (2008) In press |
| Description of Target |
This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide bind |
| Protein Interactions |
BRCA1; UBC; SUMO2; PCNA; POLK; SAMHD1; GANAB; HYOU1; SUPT5H; XRCC6; ATP6V1B2; UBD; HDAC11; MSH2; CSNK2A1; SUPT16H; MSH3; MLH1; PMS2; RAD9A; RAD1; MUTYH; HUS1; SLX4; CUL3; NEDD8; FBXO25; SIRT7; XRCC5; PRKDC; BLM; TP53; RAD51; PMS1; SMARCAD1; CHAF1A; DTL; S |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MSH6 (ARP41348_P050) antibody |
| Blocking Peptide |
For anti-MSH6 (ARP41348_P050) antibody is Catalog # AAP41348 (Previous Catalog # AAPS01507) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human MSH6 |
| Uniprot ID |
P52701 |
| Protein Name |
DNA mismatch repair protein Msh6 |
| Protein Accession # |
NP_000170 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_000179 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MSH6 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93% |
| Image 1 | Human THP1
 | WB Suggested Anti-MSH6 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: THP-1 cell lysate |
|
| Image 2 | Human, Mouse B cells
 | MSH6 antibody - N-terminal region (ARP41348_P050) validated by WB using Human B cells and Mouse B cells at 0.8 ug/ml. |
|
| Image 3 | Human colon cancer tissue
 | Sample Type: Human Colon Cancer Tissue
Primary Dilution: 1ug/mL |
|
| Image 4 | Human Tonsil
 | Sample Type: Human Tonsil TissuePrimary
Dilution: 1ug/mL |
|
