WDR5 Antibody - C-terminal region (ARP41306_P050)

• Product Number: ARP41306_P050
• Name: WDR5 Antibody - C-terminal region (ARP41306_P050)
• Protein Size (# AA): 334 amino acids
• Molecular Weight: 36kDa
• NCBI Gene Id: 11091
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: WD repeat domain 5
• Alias Symbols: SWD3, BIG-3, CFAP89
• Peptide Sequence: Synthetic peptide located within the following region: LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Description of Target: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
• Protein Interactions: RUSC1-AS1; SSX2IP; ZXDC; MBIP; CXXC1; SETD1A; HSF2; PRMT5; NFE4; KMT2D; ING2; HDAC1; SENP3; UBC; BMI1; SRPK2; CSNK2A2; CSNK1E; KDM6B; KDM6A; NEDD8; KMT2A; BARD1; UNC45A; VPS35; CSE1L; ATP6V1B2; APP; ASH2L; USP1; TTK; PPP1CB; HCFC1; TADA3; KAT2B; TADA2A; M
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Other Applications Image 1 Data: IP Suggested Anti-WDR5 antibody
  Titration: 2 ug/ml
  Positive Control: Human NT2 cell lysate
  
• Blocking Peptide: For anti-WDR5 (ARP41306_P050) antibody is Catalog # AAP41306 (Previous Catalog # AAPP22661)
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WDR5
• Uniprot ID: Q5M786
• Protein Name: WD repeat-containing protein 5
• Protein Accession #: NP_060058
• Purification: Affinity Purified
• Nucleotide Accession #: NM_017588
• Tested Species Reactivity: Human
• Gene Symbol: WDR5
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast, Zebrafish
• Application: IHC, WB, IP
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 93%
• Image 1: Human 721_B
  
  WB Suggested Anti-WDR5 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:62500
  Positive Control: 721_B cell lysate
• Image 2: Human NT2
  
  Amount and Sample Type:
  500 ug Human NT2 cell lysate
  Amount of IP Antibody:
  6 ug
  Primary Antibody:
  WDR5
  Primary Antibody Dilution:
  1:500
  Secondary Antibody:
  Goat anti-rabbit Alexa-Fluor 594
  Secondary Antibody Dilution:
  1:5000
  Gene Name:
  WDR5
  Submitted by:
  Dr. Yuzhi Chen, University of Arkansas for Medical Science
• Image 3: Human brain stems (NT2)
  
  Sample Type:
  Human brain stem cells (NT2)
  Primary Antibody Dilution:
  1:500
  Secondary Antibody:
  Goat anti-rabbit Alexa Fluor 594
  Secondary Antibody Dilution:
  1:1000
  Color/Signal Descriptions:
  Red: WDR5 Blue: DAPI
  Gene Name:
  WDR5
  Submitted by:
  Dr. Yuzhi Chen, University of Arkansas for Medical Science
• Image 4: Human HepG2 Whole Cell
  
  Host: Rabbit
  Target Name: WDR5
  Sample Tissue: Human HepG2 Whole Cell
  Antibody Dilution: 2ug/ml