| Product Number |
ARP41213_P050 |
| Product Page |
www.avivasysbio.com/sf1-antibody-c-terminal-region-arp41213-p050.html |
| Name |
SF1 Antibody - C-terminal region (ARP41213_P050) |
| Protein Size (# AA) |
638 amino acids |
| Molecular Weight |
69kDa |
| NCBI Gene Id |
7536 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Splicing factor 1 |
| Alias Symbols |
BBP, MBBP, ZFM1, ZNF162, D11S636, ZCCHC25 |
| Peptide Sequence |
Synthetic peptide located within the following region: APPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQPQQRPWW |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Rino,J., (2008) Mol. Cell. Biol. 28 (9), 3045-3057 |
| Description of Target |
SF1 contains 1 CCHC-type zinc finger and 1 KH domain. SF1 is Necessary for the ATP-dependent first step of spliceosome assembly. It binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. SF1 may act as transcription repressor.This gene encodes a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Protein Interactions |
KRTAP26-1; TRIM69; FAM168A; CIAO1; MKRN3; PSMA3; FUS; UBC; NEDD8; SUZ12; EED; RPL24; PLOD2; OSBP; NARS; GFPT1; GART; EIF4B; APBB1; SUPT5H; TROVE2; ITCH; PRPF40A; SAMHD1; XPO7; WBP4; FAF1; TCERG1; HSPH1; FARSB; GAS7; RANBP3; HIRIP3; HIST1H4A; XRCC5; U2AF2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SF1 (ARP41213_P050) antibody |
| Blocking Peptide |
For anti-SF1 (ARP41213_P050) antibody is Catalog # AAP41213 (Previous Catalog # AAPP22588) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human SF1 |
| Uniprot ID |
Q15637-2 |
| Protein Name |
Splicing factor 1 |
| Sample Type Confirmation |
SF1 is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_973724 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_201995 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SF1 |
| Predicted Species Reactivity |
Human, Mouse, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-SF1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysateSF1 is supported by BioGPS gene expression data to be expressed in Jurkat |
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