CPEB2 Antibody - N-terminal region (ARP41186_P050)

Data Sheet
 
Product Number ARP41186_P050
Product Page www.avivasysbio.com/cpeb2-antibody-n-terminal-region-arp41186-p050.html
Name CPEB2 Antibody - N-terminal region (ARP41186_P050)
Protein Size (# AA) 589 amino acids
Molecular Weight 65kDa
NCBI Gene Id 132864
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Cytoplasmic polyadenylation element binding protein 2
Description
Alias Symbols CPEB-2, CPE-BP2, hCPEB-2
Peptide Sequence Synthetic peptide located within the following region: FLQQRNSYNHHQPLLKQSPWSNHQSSGWGTGSMSWGAMHGRDHRRTGNMG
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Kurihara,Y., (2003) Biol. Reprod. 69 (1), 261-268
Description of Target CPEB2 is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids.The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CPEB2 (ARP41186_P050) antibody
Blocking Peptide For anti-CPEB2 (ARP41186_P050) antibody is Catalog # AAP41186 (Previous Catalog # AAPP22561)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CPEB2
Uniprot ID Q7Z5Q1-2
Protein Name Cytoplasmic polyadenylation element-binding protein 2
Publications

CPEB2 Is Necessary for Proper Porcine Meiotic Maturation and Embryonic Development. Int J Mol Sci. 19, (2018). 30322039

Protein Accession # NP_872291
Purification Affinity Purified
Nucleotide Accession # NM_182485
Tested Species Reactivity Human
Gene Symbol CPEB2
Predicted Species Reactivity Human, Mouse, Rat, Guinea Pig
Application WB
Predicted Homology Based on Immunogen Sequence Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%
Image 1
Human Jurkat
WB Suggested Anti-CPEB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
 

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