RAVER1 Antibody - N-terminal region (ARP41099_T100)

Data Sheet
 
Product Number ARP41099_T100
Product Page www.avivasysbio.com/raver1-antibody-n-terminal-region-arp41099-t100.html
Name RAVER1 Antibody - N-terminal region (ARP41099_T100)
Protein Size (# AA) 606 amino acids
Molecular Weight 67kDa
NCBI Gene Id 125950
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Ribonucleoprotein, PTB-binding 1
Peptide Sequence Synthetic peptide located within the following region: VTHRPPLSPKSGAEVEAGDAAERRAPEEELPPLDPEEIRKRLEHTERQFR
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Beausoleil,S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135
Description of Target RAVER1 contains 3 RRM (RNA recognition motif) domains. It cooperates with PTBP1 to modulate regulated alternative splicing events and promotes exon skipping. It cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
Protein Interactions FUS; NEDD1; CEP76; CEP72; HAUS2; CEP250; AURKB; TUBG1; TP53; PPP2R1A; LGALS3BP; CDKN1A; CDC20; AIRE; STAU1; UBC; RPA3; RPA2; RPA1; WHSC1; VCAM1; FN1; MCAT; DYNLT1; SDHA; PHKB; ABCC1; AK2; ELAVL1; SUMO2; Cnot3; TERF2; PTBP1; VCL; ACTN1; ACTN2;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-RAVER1 (ARP41099_T100) antibody
Blocking Peptide For anti-RAVER1 (ARP41099_T100) antibody is Catalog # AAP41099 (Previous Catalog # AAPY01150)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human RAVER1
Uniprot ID Q8IY67
Protein Name Ribonucleoprotein PTB-binding 1
Protein Accession # NP_597709
Purification Protein A purified
Nucleotide Accession # NM_133452
Tested Species Reactivity Human
Gene Symbol RAVER1
Predicted Species Reactivity Human, Cow, Dog, Guinea Pig, Horse, Rabbit
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 86%; Dog: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Rabbit: 86%
Image 1
Human HepG2
WB Suggested Anti-RAVER1 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate
Image 2
Human Kidney
Rabbit Anti-RAVER1Antibody
Catalog Number: ARP41099
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
 

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