| Product Number |
ARP40935_T100 |
| Product Page |
www.avivasysbio.com/exosc4-antibody-n-terminal-region-arp40935-t100.html |
| Name |
EXOSC4 Antibody - N-terminal region (ARP40935_T100) |
| Protein Size (# AA) |
245 amino acids |
| Molecular Weight |
27kDa |
| NCBI Gene Id |
54512 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Exosome component 4 |
| Alias Symbols |
SKI6, p12A, RRP41, Ski6p, RRP41A, Rrp41p, hRrp41p |
| Peptide Sequence |
Synthetic peptide located within the following region: SDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Oh,J.H., (2005) Mamm. Genome 16 (12), 942-954 |
| Description of Target |
EXOSC4 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA. It has a 3'-5' exonuclease activity. |
| Protein Interactions |
EED; TOM1; NMI; H1FX; HIST1H1E; TSEN15; GADD45GIP1; FAHD1; SMPD4; LRRC8D; EXOSC1; EXOSC3; MPZL1; SKIV2L; EXOSC10; EXOSC9; NEK1; HNRNPD; DXO; AICDA; UBC; ESR2; EXOSC5; DDX47; EXOSC2; EXOSC7; EXOSC8; PSIP1; EXOSC6; DIS3L; EXOSC4; SKIV2L2; DIS3; UPF2; MPP6; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-EXOSC4 (ARP40935_T100) antibody |
| Blocking Peptide |
For anti-EXOSC4 (ARP40935_T100) antibody is Catalog # AAP40935 (Previous Catalog # AAPS02603) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC4 |
| Uniprot ID |
Q9NPD3 |
| Protein Name |
Exosome complex component RRP41 |
| Protein Accession # |
NP_061910 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_019037 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
EXOSC4 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 93% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-EXOSC4 Antibody Titration: 5.0ug/ml
Positive Control: Jurkat cell lysate |
|
| Image 2 | Human Heart
 | Rabbit Anti-EXOSC4 Antibody
Catalog Number: ARP40935
Paraffin Embedded Tissue: Human Heart
Cellular Data: Myocardial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 3 | Human Liver
 | Rabbit Anti-EXOSC4 Antibody
Catalog Number: ARP40935
Paraffin Embedded Tissue: Human Liver
Cellular Data: Hepatocytes
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 4 | MCF7 Cell Lysate, Human Liver
 | Host: Rabbit
Target: EXOSC4
Positive control (+): MCF7 Cell Lysate (N10)
Negative control (-): Human Liver (LI)
Antibody concentration: 1ug/ml |
|
