| Product Number |
ARP40841_T100 |
| Product Page |
www.avivasysbio.com/cpsf3-antibody-c-terminal-region-arp40841-t100.html |
| Name |
CPSF3 Antibody - C-terminal region (ARP40841_T100) |
| Protein Size (# AA) |
684 amino acids |
| Molecular Weight |
75kDa |
| Subunit |
3 |
| NCBI Gene Id |
51692 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Cleavage and polyadenylation specific factor 3, 73kDa |
| Alias Symbols |
CPSF73, CPSF-73 |
| Peptide Sequence |
Synthetic peptide located within the following region: DDSILSVTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEAL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Calzado,M.A., (2004) J. Virol. 78 (13), 6846-6854 |
| Description of Target |
CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. |
| Protein Interactions |
UBC; SUMO1; WWOX; AICDA; POLR2A; NPM1; TUT1; SYMPK; CSTF2; CPSF2; PAXIP1; MDC1; BARD1; FIP1L1; POLR1E; WDR33; CPSF1; UBD; SIRT7; SMARCAD1; RRAGA; TBP; CDC73; CLP1; PAPOLA; YWHAG; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CPSF3 (ARP40841_T100) antibody |
| Blocking Peptide |
For anti-CPSF3 (ARP40841_T100) antibody is Catalog # AAP40841 (Previous Catalog # AAPS01709) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human CPSF3 |
| Uniprot ID |
Q9UKF6 |
| Protein Name |
Cleavage and polyadenylation specificity factor subunit 3 |
| Protein Accession # |
NP_057291 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_016207 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CPSF3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-CPSF3 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate |
|
| Image 2 | Human Liver
 | Rabbit Anti-CPSF3 Antibody
Catalog Number: ARP40841
Paraffin Embedded Tissue: Human Liver
Cellular Data: Liver cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
