EXOSC2 Antibody - N-terminal region (ARP40762_T100)

Data Sheet
 
Product Number ARP40762_T100
Product Page www.avivasysbio.com/exosc2-antibody-n-terminal-region-arp40762-t100.html
Name EXOSC2 Antibody - N-terminal region (ARP40762_T100)
Protein Size (# AA) 293 amino acids
Molecular Weight 32kDa
NCBI Gene Id 23404
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Exosome component 2
Alias Symbols p7, RRP4, SHRF, Rrp4p, hRrp4p
Peptide Sequence Synthetic peptide located within the following region: RKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Beausoleil,S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135
Description of Target EXOSC2 belongs to the exosome, a RNA-processing complex, which is at least involved in the 3' processing of the 7S pre-rRNA to the mature 5.8S rRNA. It exhibits a 3'-5' exoribonuclease activity.
Protein Interactions GPX1; ST6GALNAC1; MRPL48; EXOSC7; RNF8; GALNT13; ZNF408; AICDA; METTL22; UBC; UPF1; MDC1; BARD1; EXOSC5; EXOSC4; EXOSC3; DEK; RAN; EXOSC9; DIS3L; DIS3; UBD; CAND1; HDGF; MEPCE; SKIV2L2; EXOSC6; KHSRP; MPP6; EXOSC8; UPF3A; UPF2;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-EXOSC2 (ARP40762_T100) antibody
Blocking Peptide For anti-EXOSC2 (ARP40762_T100) antibody is Catalog # AAP40762 (Previous Catalog # AAPY01014)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC2
Uniprot ID Q13868
Protein Name Exosome complex component RRP4
Sample Type Confirmation

EXOSC2 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_055100
Purification Protein A purified
Nucleotide Accession # NM_014285
Tested Species Reactivity Human
Gene Symbol EXOSC2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 79%; Dog: 86%; Guinea Pig: 85%; Horse: 79%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 91%; Rat: 93%
Image 1
Human Jurkat
WB Suggested Anti-EXOSC2 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysateEXOSC2 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
Image 2
Human Lung
Rabbit Anti-EXOSC2 antibody
Catalog Number: ARP40762
Paraffin Embedded Tissue: Human Lung cell Cellular Data: alveolar cell of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
 

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