| Product Number |
ARP40753_T100 |
| Product Page |
www.avivasysbio.com/ppp1r8-antibody-n-terminal-region-arp40753-t100.html |
| Name |
PPP1R8 Antibody - N-terminal region (ARP40753_T100) |
| Protein Size (# AA) |
351 amino acids |
| Molecular Weight |
39kDa |
| NCBI Gene Id |
5511 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Protein phosphatase 1, regulatory subunit 8 |
| Alias Symbols |
ARD1, ARD-1, NIPP1, NIPP-1, PRO2047 |
| Peptide Sequence |
Synthetic peptide located within the following region: THGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lesage,B., (2004) J. Biol. Chem. 279 (53), 55978-55984 |
| Description of Target |
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. |
| Protein Interactions |
APPBP2; UBC; FBXO25; HMGA1; WDR77; CTNNBL1; PPIL1; PPP1CC; PPP1CA; NF2; APP; SF3A2; Cep72; PPP1CB; SUZ12; RBBP4; EZH2; EED; RBM48; SF3B1; SETDB1; MELK; HDAC2; C14orf1; STC2; CDC5L; CRMP1; PRKACA; GBP2; LYN; CSNK2A2; CSNK2A1; NME2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PPP1R8 (ARP40753_T100) antibody |
| Blocking Peptide |
For anti-PPP1R8 (ARP40753_T100) antibody is Catalog # AAP40753 (Previous Catalog # AAPY01005) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human PPP1R8 |
| Uniprot ID |
Q12972 |
| Protein Name |
Nuclear inhibitor of protein phosphatase 1 |
| Sample Type Confirmation |
PPP1R8 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
NP_054829 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_014110 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PPP1R8 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
| Image 1 | Human HepG2
 | WB Suggested Anti-PPP1R8 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysatePPP1R8 is supported by BioGPS gene expression data to be expressed in HepG2 |
|
| Image 2 | Human Lung
 | Rabbit Anti-PPP1R8 antibody
Catalog Number: ARP40753
Paraffin Embedded Tissue: Human Lung cell Cellular Data: alveolar cell of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
