ADAT1 Antibody - C-terminal region (ARP40718_P050)

Data Sheet
 
Product Number ARP40718_P050
Product Page www.avivasysbio.com/adat1-antibody-c-terminal-region-arp40718-p050.html
Name ADAT1 Antibody - C-terminal region (ARP40718_P050)
Protein Size (# AA) 502 amino acids
Molecular Weight 55kDa
NCBI Gene Id 23536
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Adenosine deaminase, tRNA-specific 1
Alias Symbols HADAT1
Peptide Sequence Synthetic peptide located within the following region: LFRSFQKLLSRIARDKWPHSLRVQKLDTYQEYKEAASSYQEAWSTLRKQV
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Maas,S., (1999) Proc. Natl. Acad. Sci. U.S.A. 96 (16), 8895-8900
Description of Target ADAT1 is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, the family participates in the pre-mRNA editing of nuclear transcripts. ADAT1, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA.This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA.
Protein Interactions UBC; ELAVL1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ADAT1 (ARP40718_P050) antibody
Blocking Peptide For anti-ADAT1 (ARP40718_P050) antibody is Catalog # AAP40718 (Previous Catalog # AAPY00970)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human ADAT1
Uniprot ID Q9BUB4
Protein Name tRNA-specific adenosine deaminase 1
Protein Accession # NP_036223
Purification Affinity Purified
Nucleotide Accession # NM_012091
Tested Species Reactivity Human
Gene Symbol ADAT1
Predicted Species Reactivity Human, Mouse, Rat, Dog, Guinea Pig, Horse
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Dog: 79%; Guinea Pig: 85%; Horse: 86%; Human: 100%; Mouse: 86%; Rat: 93%
Image 1
Human Stomach
Rabbit Anti-ADAT1 Antibody
Catalog Number: ARP40718
Paraffin Embedded Tissue: Human Stomach
Cellular Data: Epithelial cells of fundic gland
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Image 2
Human Thymus
WB Suggested Anti-ADAT1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Thymus
 

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