Product Number |
ARP40709_P050 |
Product Page |
www.avivasysbio.com/irak3-antibody-c-terminal-region-arp40709-p050.html |
Name |
IRAK3 Antibody - C-terminal region (ARP40709_P050) |
Protein Size (# AA) |
596 amino acids |
Molecular Weight |
66kDa |
NCBI Gene Id |
11213 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Interleukin-1 receptor-associated kinase 3 |
Alias Symbols |
ASRT5, IRAKM |
Peptide Sequence |
Synthetic peptide located within the following region: NTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
del (2005) J. Immunol. 174 (5), 3032-3040 |
Description of Target |
IRAK3 contains 1 protein kinase domain and 1 death domain and belongs to the Ser/Thr protein kinase family, Pelle subfamily. It inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. |
Protein Interactions |
CDCA5; NSA2; LDB1; NTRK3; NONO; HSP90AA1; HOXB7; FOLR1; ECM1; COPB1; CD14; ATP6V0B; ADH1B; IRAK1; UBC; IRAK4; IRAK2; TICAM2; IRAK3; TRAF6; MYD88; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-IRAK3 (ARP40709_P050) antibody |
Blocking Peptide |
For anti-IRAK3 (ARP40709_P050) antibody is Catalog # AAP40709 (Previous Catalog # AAPY00961) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human IRAK3 |
Uniprot ID |
Q9Y616 |
Protein Name |
Interleukin-1 receptor-associated kinase 3 |
Protein Accession # |
NP_009130 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_007199 |
Tested Species Reactivity |
Human |
Gene Symbol |
IRAK3 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 86%; Rabbit: 79%; Rat: 86% |
Image 1 | Human HepG2
| WB Suggested Anti-IRAK3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: HepG2 cell lysate |
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