NUDT21 Antibody - N-terminal region (ARP40695_T100)

Data Sheet
 
Product Number ARP40695_T100
Product Page www.avivasysbio.com/nudt21-antibody-n-terminal-region-arp40695-t100.html
Name NUDT21 Antibody - N-terminal region (ARP40695_T100)
Protein Size (# AA) 227 amino acids
Molecular Weight 25kDa
Subunit 5
NCBI Gene Id 11051
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Nudix (nucleoside diphosphate linked moiety X)-type motif 21
Alias Symbols CPSF5, CFIM25
Peptide Sequence Synthetic peptide located within the following region: TGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSV
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Dettwiler,S., (2004) J. Biol. Chem. 279 (34), 35788-35797
Description of Target NUDT21 is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors.The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides.
Protein Interactions CPSF7; NUDT21; HUWE1; TRIM27; GOLGA2; FUS; UBC; STAU1; FXR2; RPA3; RPA2; RPA1; ASB12; RNF2; EZH2; ITCH; WWOX; TCERG1; CARM1; EIF3A; RPL18; NEDD4; EIF3CL; PRPF4B; SRPK2; SRPK1; CPSF6; NPM1; CD81; FN1; VCAM1; ITGA4; SMURF1; S100A13; RPS3; HDAC2; SKIV2L2; FA
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-NUDT21 (ARP40695_T100) antibody
Blocking Peptide For anti-NUDT21 (ARP40695_T100) antibody is Catalog # AAP40695 (Previous Catalog # AAPY00947)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human NUDT21
Uniprot ID O43809
Protein Name Cleavage and polyadenylation specificity factor subunit 5
Protein Accession # NP_008937
Purification Protein A purified
Nucleotide Accession # NM_007006
Tested Species Reactivity Human
Gene Symbol NUDT21
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Human Intestine
Rabbit Anti-NUDT21 Antibody
Catalog Number: ARP40695
Paraffin Embedded Tissue: Human Intestine
Cellular Data: Epithelial cells of intestinal villas
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Image 2
Human HepG2
WB Suggested Anti-NUDT21 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate
 

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