| Product Number |
ARP40669_T100 |
| Product Page |
www.avivasysbio.com/fars2-antibody-n-terminal-region-arp40669-t100.html |
| Name |
FARS2 Antibody - N-terminal region (ARP40669_T100) |
| Protein Size (# AA) |
451 amino acids |
| Molecular Weight |
50kDa |
| NCBI Gene Id |
10667 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Phenylalanyl-tRNA synthetase 2, mitochondrial |
| Alias Symbols |
FARS1, PheRS, SPG77, COXPD14, HSPC320, mtPheRS |
| Peptide Sequence |
Synthetic peptide located within the following region: VELLGKSYPQDDHSNLTRKVLTRVGRNLHNQQHHPLWLIKERVKEHFYKQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Brandenberger,R., (2004) Nat. Biotechnol. 22 (6), 707-716 |
| Description of Target |
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS2 is a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a single polypeptide chain, unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm.Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS1 encodes a mitochondrially-located phenylalanine-tRNA synthetase (PheRS) which consists of a single polypeptide chain unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and the eukaryotic cytoplasm. |
| Protein Interactions |
TRIM27; KRT31; KRT13; RCBTB2; NOTCH2NL; KRTAP10-3; KRTAP10-5; KRTAP10-9; KRTAP10-7; KRT40; CMTM5; HMBOX1; TRIM54; AGTRAP; ADAMTSL4; APPL1; IKZF3; MID2; CALCOCO2; STX11; MKRN3; TFCP2; TADA2A; SUMO1; UBC; NEDD8; CUL3; ISG15; ICT1; USP45; G3BP2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-FARS2 (ARP40669_T100) antibody |
| Blocking Peptide |
For anti-FARS2 (ARP40669_T100) antibody is Catalog # AAP40669 (Previous Catalog # AAPY00921) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FARS2 |
| Uniprot ID |
O95363 |
| Protein Name |
Phenylalanine--tRNA ligase, mitochondrial |
| Protein Accession # |
NP_006558 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_006567 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
FARS2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 92%; Guinea Pig: 85%; Horse: 83%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 93% |
| Image 1 | Transfected 293T
 | WB Suggested Anti-FARS2 Antibody Titration: 5.0ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T |
|
| Image 2 | Human Muscle
 | Rabbit Anti-FARS2 Antibody
Catalog Number: ARP40669
Paraffin Embedded Tissue: Human Muscle
Cellular Data: Skeletal muscle cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
