| Product Number |
ARP40663_P050 |
| Product Page |
www.avivasysbio.com/khdrbs3-antibody-c-terminal-region-arp40663-p050.html |
| Name |
KHDRBS3 Antibody - C-terminal region (ARP40663_P050) |
| Protein Size (# AA) |
346 amino acids |
| Molecular Weight |
38kDa |
| NCBI Gene Id |
10656 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
KH domain containing, RNA binding, signal transduction associated 3 |
| Alias Symbols |
Etle, SALP, SLM2, SLM-2, TSTAR, T-STAR, etoile |
| Peptide Sequence |
Synthetic peptide located within the following region: EQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Cohen,C.D., (2005) J. Am. Soc. Nephrol. 16 (7), 1958-1965 |
| Description of Target |
As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression. |
| Protein Interactions |
YTHDC1; DMRT3; MARK4; NCOA5; PRPF31; BAHD1; KHDRBS3; INPP5D; UBC; BMI1; NELFB; RBM7; PSMF1; SIAH1; HNRNPK; KHDRBS2; CCDC33; PTBP2; U2AF2; KHDRBS1; SNRPC; HNRNPC; FUS; FBXO32; SERPINB5; RBBP6; CACNA1A; RPAP2; ZNF408; LNX1; SGSM2; SRSF9; NUDT18; PRMT1; RBMY |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-KHDRBS3 (ARP40663_P050) antibody |
| Blocking Peptide |
For anti-KHDRBS3 (ARP40663_P050) antibody is Catalog # AAP40663 (Previous Catalog # AAPY00915) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human KHDRBS3 |
| Uniprot ID |
O75525 |
| Protein Name |
KH domain-containing, RNA-binding, signal transduction-associated protein 3 |
| Protein Accession # |
NP_006549 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006558 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
KHDRBS3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-KHDRBS3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate |
|
| Image 2 | Human Kidney
 | Rabbit Anti-KHDRBS3 Antibody
Catalog Number: ARP40663
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
