IGF2BP1 Antibody - N-terminal region (ARP40658_P050)

• Product Number: ARP40658_P050
• Name: IGF2BP1 Antibody - N-terminal region (ARP40658_P050)
• Protein Size (# AA): 577 amino acids
• Molecular Weight: 63kDa
• NCBI Gene Id: 10642
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Insulin-like growth factor 2 mRNA binding protein 1
• Description:
  View product citations for IGF2BP1 Antibody - N-terminal region (ARP40658_P050) on CiteAb
• Alias Symbols: IMP1, ZBP1, CRDBP, IMP-1, CRD-BP, VICKZ1
• Peptide Sequence: Synthetic peptide located within the following region: PDEQIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPT
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Ioannidis,P., (2005) J. Biol. Chem. 280 (20), 20086-20093
• Description of Target: IGF2BP1 is a member of the IGF-II mRNA-binding protein (IMP) family. The protein contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation.This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation.This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Protein Interactions: HAUS2; TUBGCP2; TUBGCP3; TP53; AURKA; CDKN1A; TUBGCP4; CEP250; IVNS1ABP; STAU1; UBC; WWOX; PARK2; FBXO6; BAG3; PAN2; VCAM1; ITGA4; IFIT1; GRB2; FN1; CBX6; CBX8; SYNCRIP; BIRC2; CAND1; COPS5; CUL1; CUL2; CUL3; CUL4A; CUL4B; CUL5; NEDD8; gag; BTRC; ARRB2; Y
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-IGF2BP1 (ARP40658_P050) antibody is Catalog # AAP40658 (Previous Catalog # AAPY00910)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IGF2BP1
• Uniprot ID: Q9NZI8
• Protein Name: Insulin-like growth factor 2 mRNA-binding protein 1
• Publications:

  Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. Mol Cell. 74, 701-712.e9 (2019). 30948266

• Protein Accession #: NP_006537
• Purification: Affinity Purified
• Nucleotide Accession #: NM_006546
• Tested Species Reactivity: Human, Rat
• Gene Symbol: IGF2BP1
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep
• Application: IHC, WB
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%
• Image 1: Human HepG2
  
  WB Suggested Anti-IGF2BP1 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:12500
  Positive Control: HepG2 cell lysate
• Image 2: Human Lung
  
  Researcher:Haodong Xu. Department of Pathology, University of Rochester medical Center
  Application: IHC
  Species+tissue/cell type: Human lung adenocarcinoma
  Primary antibody dilution: 1:300
  Secondary antibody: Anti-rabbit-linker, Fbex-HRP
  Secondary antibody dilution: NOT FOUND
• Image 3: Human lung adenocarcinoma
  
  Sample Type:
  Human lung adenocarcinoma
  Primary Antibody Dilution:
  1:300
  Secondary Antibody:
  Anti-rabbit-linker, Fbex-HRP
  Secondary Antibody Dilution:
  NOT FOUND
  Color/Signal Descriptions:
  Brown: IGFBP1 Blue: Nuclei
  Gene Name:
  IGF2BP1
  Submitted by:
  Haodong Xu. Department of Pathology, University of Rochester medical Center
• Image 4: Rat Skeletal Muscle
  
  Host: Rat
  Target Name: IGF2BP1
  Sample Tissue: Rat Skeletal Muscle
  Antibody Dilution: 1ug/ml
• Image 5: Rat Skeletal Muscle
  
  Host: Rabbit
  Target Name: IGF2BP1
  Sample Tissue: Rat Skeletal Muscle
  Antibody Dilution: 1ug/ml