EMG1 Antibody - N-terminal region (ARP40636_P050)

Data Sheet
 
Product Number ARP40636_P050
Product Page www.avivasysbio.com/emg1-antibody-n-terminal-region-arp40636-p050.html
Name EMG1 Antibody - N-terminal region (ARP40636_P050)
Protein Size (# AA) 244 amino acids
Molecular Weight 27kDa
NCBI Gene Id 10436
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name EMG1 nucleolar protein homolog (S. cerevisiae)
Alias Symbols C2F, NEP1, Grcc2f
Peptide Sequence Synthetic peptide located within the following region: SLETVKVGKTYELLNCDKHKSILLKNGRDPGEARPDITHQSLLMLMDSPL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Bernstein,K.A., (2004) Eukaryotic Cell 3 (6), 1619-1626
Description of Target EMG1 involved in 40S ribosomal subunit biogenesis. It seems to play a role a methylation reaction in pre-rRNA processing.
Protein Interactions FAM74A4; UBC; RPA3; RPA2; RPA1; EED; rev; HECW2; IL7R; FN1; BYSL; APP; NEDD8; SLC25A38; NAT6; PSMB7; KHDRBS1; PSME1; HIVEP1; CTSE; ANXA3;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-EMG1 (ARP40636_P050) antibody
Blocking Peptide For anti-EMG1 (ARP40636_P050) antibody is Catalog # AAP40636 (Previous Catalog # AAPP22787)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human EMG1
Uniprot ID Q92979
Protein Name Ribosomal RNA small subunit methyltransferase NEP1
Publications

Armistead, J. et al. Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome. Am. J. Hum. Genet. 84, 728-39 (2009). 19463982

Sample Type Confirmation

EMG1 is supported by BioGPS gene expression data to be expressed in HepG2

Protein Accession # NP_006322
Purification Affinity Purified
Nucleotide Accession # NM_006331
Tested Species Reactivity Human
Gene Symbol EMG1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 93%; Rabbit: 92%; Rat: 93%; Zebrafish: 79%
Image 1
Human HepG2
WB Suggested Anti-EMG1 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysateEMG1 is supported by BioGPS gene expression data to be expressed in HepG2
Image 2
Human Kidney
Rabbit Anti-EMG1 Antibody
Catalog Number: ARP40636
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
 

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