Product Number |
ARP40589_P050 |
Product Page |
www.avivasysbio.com/kars-antibody-c-terminal-region-arp40589-p050.html |
Name |
KARS Antibody - C-terminal region (ARP40589_P050) |
Protein Size (# AA) |
597 amino acids |
Molecular Weight |
66kDa |
NCBI Gene Id |
3735 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Lysyl-tRNA synthetase |
Alias Symbols |
KRS, KARS, KARS2, LEPID, CMTRIB, DEAPLE, DFNB89 |
Peptide Sequence |
Synthetic peptide located within the following region: GMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Halwani,R., (2004) J. Virol. 78 (14), 7553-7564 |
Description of Target |
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. |
Protein Interactions |
AIMP2; SUMO2; SUMO3; MDM2; UBC; SUMO1; NEDD8; STAT1; SSB; RPL21; RPL19; RPL17; NAP1L4; HSPA4; GPX1; CARS; APEH; CAND1; RANBP6; RPL36; JMJD6; NUDC; IPO7; AIMP1; SH3RF2; FBXO6; vpr; MSK1; gag; FN1; TRMT1; MRPS18B; UBE2S; CCT8; EEF1E1; VBP1; UBA1; RARS; QARS |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-KARS (ARP40589_P050) antibody |
Blocking Peptide |
For anti-KARS (ARP40589_P050) antibody is Catalog # AAP40589 (Previous Catalog # AAPP22349) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human KARS |
Uniprot ID |
Q15046 |
Protein Name |
Lysine--tRNA ligase |
Sample Type Confirmation |
KARS is strongly supported by BioGPS gene expression data to be expressed in HepG2 |
Protein Accession # |
NP_005539 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_005548 |
Tested Species Reactivity |
Human |
Gene Symbol |
KARS |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Rabbit |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Guinea Pig: 85%; Horse: 88%; Human: 100%; Mouse: 79%; Pig: 86%; Rabbit: 86%; Rat: 86% |
Image 1 | Human HepG2
| WB Suggested Anti-KARS Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysateKARS is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells |
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Image 2 | Human Intestine
| Rabbit Anti-KARS Antibody Catalog Number: ARP40589 Paraffin Embedded Tissue: Human Intestine Cellular Data: Epithelial cells of intestinal villas Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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Image 3 | Human Bronchial Epithelial Tissue
| KARS antibody - C-terminal region (ARP40589_P050)
Catalog Number: ARP40589_P050
Formalin Fixed Paraffin Embedded Tissue: Human Bronchial Epithelial Tissue
Observed Staining: Cytoplasm of bronchial epithelial tissue
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
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