Product Number |
ARP40576_T100 |
Product Page |
www.avivasysbio.com/rbm8a-antibody-n-terminal-region-arp40576-t100.html |
Name |
RBM8A Antibody - N-terminal region (ARP40576_T100) |
Protein Size (# AA) |
174 amino acids |
Molecular Weight |
19kDa |
NCBI Gene Id |
9939 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
RNA binding motif protein 8A |
Alias Symbols |
TAR, Y14, RBM8, ZNRP, RBM8B, ZRNP1, BOV-1A, BOV-1B, BOV-1C, MDS014, DEL1q21.1, C1DELq21.1 |
Peptide Sequence |
Synthetic peptide located within the following region: LHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDS |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Hsu,Ia.W., (2005) J. Biol. Chem. 280 (41), 34507-34512 |
Description of Target |
RBM8A is a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events.This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites. |
Protein Interactions |
MAGOHB; MAGOH; UBC; SUZ12; RNF2; PARK2; SRPK2; SRPK1; FBXO25; tat; UPF3B; SMG9; SMG8; PABPC1; UPF2; SMG5; SMG1; RUVBL2; RBM8A; SMG7; EIF4A3; TTI1; RUVBL1; UPF1; NCBP2; TOE1; SF3B2; RPS16; RPL11; HBB; GSPT1; ZFP36L1; UNC119B; SLIRP; LSM2; CIAPIN1; TFCP2L1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-RBM8A (ARP40576_T100) antibody |
Blocking Peptide |
For anti-RBM8A (ARP40576_T100) antibody is Catalog # AAP40576 (Previous Catalog # AAPP22752) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human RBM8A |
Uniprot ID |
Q9Y5S9 |
Protein Name |
RNA-binding protein 8A |
Sample Type Confirmation |
There is BioGPS gene expression data showing that RBM8A is expressed in Jurkat |
Protein Accession # |
NP_005096 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_005105 |
Tested Species Reactivity |
Human |
Gene Symbol |
RBM8A |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 82%; Rabbit: 82%; Rat: 100%; Zebrafish: 100% |
Image 1 | Human Lung
| Rabbit Anti-RBM8A Antibody Catalog Number: ARP40576 Paraffin Embedded Tissue: Human alveolar cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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Image 2 | Human Jurkat
| WB Suggested Anti-RBM8A Antibody Titration: 1.25ug/ml Positive Control: Jurkat cell lysateThere is BioGPS gene expression data showing that RBM8A is expressed in Jurkat |
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Image 3 | Human Heart
| Rabbit Anti-RBM8A Antibody Catalog Number: ARP40576 Paraffin Embedded Tissue: Human Heart Cellular Data: Myocardial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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