RBM8A Antibody - N-terminal region (ARP40576_T100)

Data Sheet
 
Product Number ARP40576_T100
Product Page www.avivasysbio.com/rbm8a-antibody-n-terminal-region-arp40576-t100.html
Name RBM8A Antibody - N-terminal region (ARP40576_T100)
Protein Size (# AA) 174 amino acids
Molecular Weight 19kDa
NCBI Gene Id 9939
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name RNA binding motif protein 8A
Alias Symbols TAR, Y14, RBM8, ZNRP, RBM8B, ZRNP1, BOV-1A, BOV-1B, BOV-1C, MDS014, DEL1q21.1, C1DELq21.1
Peptide Sequence Synthetic peptide located within the following region: LHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDS
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Hsu,Ia.W., (2005) J. Biol. Chem. 280 (41), 34507-34512
Description of Target RBM8A is a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events.This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.
Protein Interactions MAGOHB; MAGOH; UBC; SUZ12; RNF2; PARK2; SRPK2; SRPK1; FBXO25; tat; UPF3B; SMG9; SMG8; PABPC1; UPF2; SMG5; SMG1; RUVBL2; RBM8A; SMG7; EIF4A3; TTI1; RUVBL1; UPF1; NCBP2; TOE1; SF3B2; RPS16; RPL11; HBB; GSPT1; ZFP36L1; UNC119B; SLIRP; LSM2; CIAPIN1; TFCP2L1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-RBM8A (ARP40576_T100) antibody
Blocking Peptide For anti-RBM8A (ARP40576_T100) antibody is Catalog # AAP40576 (Previous Catalog # AAPP22752)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human RBM8A
Uniprot ID Q9Y5S9
Protein Name RNA-binding protein 8A
Sample Type Confirmation

There is BioGPS gene expression data showing that RBM8A is expressed in Jurkat

Protein Accession # NP_005096
Purification Protein A purified
Nucleotide Accession # NM_005105
Tested Species Reactivity Human
Gene Symbol RBM8A
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 82%; Rabbit: 82%; Rat: 100%; Zebrafish: 100%
Image 1
Human Lung
Rabbit Anti-RBM8A Antibody
Catalog Number: ARP40576
Paraffin Embedded Tissue: Human alveolar cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Image 2
Human Jurkat
WB Suggested Anti-RBM8A Antibody Titration: 1.25ug/ml
Positive Control: Jurkat cell lysateThere is BioGPS gene expression data showing that RBM8A is expressed in Jurkat
Image 3
Human Heart
Rabbit Anti-RBM8A Antibody
Catalog Number: ARP40576
Paraffin Embedded Tissue: Human Heart
Cellular Data: Myocardial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
 

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