PRPF3 Antibody - N-terminal region (ARP40543_P050)

Data Sheet
 
Product Number ARP40543_P050
Product Page www.avivasysbio.com/prpf3-antibody-n-terminal-region-arp40543-p050.html
Name PRPF3 Antibody - N-terminal region (ARP40543_P050)
Protein Size (# AA) 683 amino acids
Molecular Weight 75kDa
NCBI Gene Id 9129
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)
Alias Symbols PRP3, RP18, HPRP3, Prp3p, HPRP3P, SNRNP90
Peptide Sequence Synthetic peptide located within the following region: VDKLFEAVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRR
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Rual,J.F., (2005) Nature 437 (7062), 1173-1178
Description of Target The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs.The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs.[supplied by OMIM].
Protein Interactions FAM9B; TRIM39; SART3; CEP250; AURKB; UBC; TUBG1; LIN28A; MEPCE; WWOX; WBP4; TARDBP; MMS19; FRA10AC1; SNIP1; NKAP; CTNNBL1; ZCCHC10; U2AF2; SF3B2; SLU7; SMNDC1; RBM39; PRPF3; PCBP1; MFAP1; PATL1; RBM25; NOP58; LSM1; PABPC1; PRPF6; NNT; SRRM2; SUPT16H; SF3A
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-PRPF3 (ARP40543_P050) antibody
Blocking Peptide For anti-PRPF3 (ARP40543_P050) antibody is Catalog # AAP40543 (Previous Catalog # AAPP22303)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human PRPF3
Uniprot ID O43395
Protein Name U4/U6 small nuclear ribonucleoprotein Prp3
Protein Accession # NP_004689
Purification Affinity Purified
Nucleotide Accession # NM_004698
Tested Species Reactivity Human
Gene Symbol PRPF3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Image 1
Human HepG2
WB Suggested Anti-PRPF3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
 

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