| Product Number |
ARP40512_T100 |
| Product Page |
www.avivasysbio.com/tarbp2-antibody-n-terminal-region-arp40512-t100.html |
| Name |
TARBP2 Antibody - N-terminal region (ARP40512_T100) |
| Protein Size (# AA) |
74 amino acids |
| Molecular Weight |
8kDa |
| Subunit |
TARBP2 |
| NCBI Gene Id |
6895 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
TAR (HIV-1) RNA binding protein 2 |
| Alias Symbols |
LOQS, TRBP, TRBP1, TRBP2 |
| Peptide Sequence |
Synthetic peptide located within the following region: ANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCT |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Bannwarth,S., J. Biol. Chem. 276 (52), 48803-48813 (2001) |
| Description of Target |
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARBP2 binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. |
| Protein Interactions |
TCEANC; STRBP; ZNF346; PRKRA; TARBP2; RRP12; RRP1B; POP1; CEBPZ; RRP9; AGO3; C1orf35; DDX50; NOC3L; TSR1; DDX27; AKAP17A; TCOF1; SRPR; SRP72; SRP54; TRMT1; SDAD1; RBM28; GPATCH4; HP1BP3; AGO2; DICER1; NUDT18; AGO1; APP; TOP1; CUL3; VAV2; NEDD4L; EIF2AK2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-TARBP2 (ARP40512_T100) antibody |
| Blocking Peptide |
For anti-TARBP2 (ARP40512_T100) antibody is Catalog # AAP40512 (Previous Catalog # AAPP22279) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human TARBP2 |
| Uniprot ID |
Q8WY33 |
| Protein Name |
RISC-loading complex subunit TARBP2 |
| Protein Accession # |
AAL55731 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_004178 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
TARBP2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-TARBP2 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate |
|
