Product Number |
ARP40501_P050 |
Product Page |
www.avivasysbio.com/eif2s2-antibody-n-terminal-region-arp40501-p050.html |
Name |
EIF2S2 Antibody - N-terminal region (ARP40501_P050) |
Protein Size (# AA) |
333 amino acids |
Molecular Weight |
38kDa |
Subunit |
2 |
NCBI Gene Id |
8894 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
Alias Symbols |
EIF2, EIF2B, PPP1R67, EIF2beta, eIF-2-beta |
Peptide Sequence |
Synthetic peptide located within the following region: DEMIFDPTMSKKKKKKKKPFMLDEEGDTQTEETQPSETKEVEPEPTEDKD |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Olsen,J.V., (2006) Cell 127 (3), 635-648 |
Description of Target |
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Protein Interactions |
UBC; SUMO2; SUMO3; RPA3; RPA2; RPA1; RNF2; SUZ12; rev; GCN1L1; EIF2S1; HMGA1; MMS19; UPF1; CSNK2B; CSNK2A1; PAXIP1; APP; CAND1; HDGF; DCC; H2AFX; KIAA1377; CCDC90B; ZBTB16; PLEKHM1; EIF2B4; EIF2B1; EIF2B3; EIF4G2; UNC119; EIF2B5; CRMP1; EIF5; PRKDC; NCK1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-EIF2S2 (ARP40501_P050) antibody |
Blocking Peptide |
For anti-EIF2S2 (ARP40501_P050) antibody is Catalog # AAP40501 (Previous Catalog # AAPP22708) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human EIF2S2 |
Uniprot ID |
P20042 |
Protein Name |
Eukaryotic translation initiation factor 2 subunit 2 |
Protein Accession # |
NP_003899 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_003908 |
Tested Species Reactivity |
Human |
Gene Symbol |
EIF2S2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 100% |
Image 1 | Human HepG2
| WB Suggested Anti-EIF2S2 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cell lysate |
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