Product Number |
ARP40456_T100 |
Product Page |
www.avivasysbio.com/srp19-antibody-middle-region-arp40456-t100.html |
Name |
SRP19 Antibody - middle region (ARP40456_T100) |
Protein Size (# AA) |
144 amino acids |
Molecular Weight |
16kDa |
NCBI Gene Id |
6728 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Signal recognition particle 19kDa |
Peptide Sequence |
Synthetic peptide located within the following region: LCLVQFPSRKSVMLYAAEMIPKLKTRTQKTGGADQSLQQGEGSKKGKGKK |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Kuglstatter,A., (2002) Nat. Struct. Biol. 9 (10), 740-744 |
Description of Target |
SRP19 belongs to the SRP19 family. It is signal-recognition-particle assembly and binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. |
Protein Interactions |
STAM2; ACTN1; BAG3; SMN1; MDN1; ZC3H11A; EIF4A3; ZFAND5; UBC; IPO8; IPO7; SRP54; TNPO1; KPNA1; IPO5; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SRP19 (ARP40456_T100) antibody |
Blocking Peptide |
For anti-SRP19 (ARP40456_T100) antibody is Catalog # AAP40456 (Previous Catalog # AAPP22224) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human SRP19 |
Uniprot ID |
P09132 |
Protein Name |
Signal recognition particle 19 kDa protein |
Publications |
Arana-Argáez, V. E. et al. Inhibitors of MAPK pathway ERK1/2 or p38 prevent the IL-1{beta}-induced up-regulation of SRP72 autoantigen in Jurkat cells. J. Biol. Chem. 285, 32824-33 (2010). 20729213 |
Sample Type Confirmation |
SRP19 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_003126 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_003135 |
Tested Species Reactivity |
Human |
Gene Symbol |
SRP19 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 85%; Rat: 92%; Zebrafish: 77% |
Image 1 | Human Jurkat
| WB Suggested Anti-SRP19 Antibody Titration: 1.25ug/ml ELISA Titer: 1:1562500 Positive Control: Jurkat cell lysateSRP19 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
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Image 2 | Human Skin
| Rabbit Anti-SRP19 Antibody Catalog Number: ARP40456 Paraffin Embedded Tissue: Human Skin Cellular Data: Squamous epithelial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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