Product Number |
ARP40359_T100 |
Product Page |
www.avivasysbio.com/eif4b-antibody-c-terminal-region-arp40359-t100.html |
Name |
EIF4B Antibody - C-terminal region (ARP40359_T100) |
Protein Size (# AA) |
611 amino acids |
Molecular Weight |
67kDa |
NCBI Gene Id |
1975 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Eukaryotic translation initiation factor 4B |
Alias Symbols |
EIF-4B, PRO1843 |
Peptide Sequence |
Synthetic peptide located within the following region: NPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQ |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Suzuki,Y., (2004) Genome Res. 14 (9), 1711-1718 |
Description of Target |
IF4B contains 1 RRM (RNA recognition motif) domain and is required for the binding of mRNA to ribosomes. Functions of EIF4B are in close association with EEF4-F and EIF4-A. It binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP and promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. |
Protein Interactions |
UBC; ASB2; ZBTB1; SAMHD1; XPO7; SEC23A; PRMT3; CUL4B; USP11; SF1; XRCC5; OSBP; NARS; Stk11; CTNNA1; PARK2; FBXO6; PAN2; CSNK2A1; EIF4A3; YWHAE; MAGOH; SMURF1; NUP107; PHAX; SLC4A1AP; CCT6B; NUP153; POLR1C; RPL29; MYH9; EIF4G2; EIF4G1; EIF4A1; CSTF2; CUL3; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-EIF4B (ARP40359_T100) antibody |
Blocking Peptide |
For anti-EIF4B (ARP40359_T100) antibody is Catalog # AAP40359 (Previous Catalog # AAPP22103) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human EIF4B |
Uniprot ID |
P23588 |
Protein Name |
Eukaryotic translation initiation factor 4B |
Sample Type Confirmation |
EIF4B is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_001408 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001417 |
Tested Species Reactivity |
Human |
Gene Symbol |
EIF4B |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 79%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86% |
Image 1 | Human Jurkat
| WB Suggested Anti-EIF4B Antibody Titration: 1.25ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysateEIF4B is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
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Image 2 | Human Heart
| Rabbit Anti-EIF4B Antibody Catalog Number: ARP40359 Paraffin Embedded Tissue: Human Heart Cellular Data: Myocardial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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