EIF4B Antibody - C-terminal region (ARP40359_T100)

Data Sheet
 
Product Number ARP40359_T100
Product Page www.avivasysbio.com/eif4b-antibody-c-terminal-region-arp40359-t100.html
Name EIF4B Antibody - C-terminal region (ARP40359_T100)
Protein Size (# AA) 611 amino acids
Molecular Weight 67kDa
NCBI Gene Id 1975
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Eukaryotic translation initiation factor 4B
Alias Symbols EIF-4B, PRO1843
Peptide Sequence Synthetic peptide located within the following region: NPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQ
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Suzuki,Y., (2004) Genome Res. 14 (9), 1711-1718
Description of Target IF4B contains 1 RRM (RNA recognition motif) domain and is required for the binding of mRNA to ribosomes. Functions of EIF4B are in close association with EEF4-F and EIF4-A. It binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP and promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Protein Interactions UBC; ASB2; ZBTB1; SAMHD1; XPO7; SEC23A; PRMT3; CUL4B; USP11; SF1; XRCC5; OSBP; NARS; Stk11; CTNNA1; PARK2; FBXO6; PAN2; CSNK2A1; EIF4A3; YWHAE; MAGOH; SMURF1; NUP107; PHAX; SLC4A1AP; CCT6B; NUP153; POLR1C; RPL29; MYH9; EIF4G2; EIF4G1; EIF4A1; CSTF2; CUL3;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-EIF4B (ARP40359_T100) antibody
Blocking Peptide For anti-EIF4B (ARP40359_T100) antibody is Catalog # AAP40359 (Previous Catalog # AAPP22103)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human EIF4B
Uniprot ID P23588
Protein Name Eukaryotic translation initiation factor 4B
Sample Type Confirmation

EIF4B is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_001408
Purification Protein A purified
Nucleotide Accession # NM_001417
Tested Species Reactivity Human
Gene Symbol EIF4B
Predicted Species Reactivity Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 79%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86%
Image 1
Human Jurkat
WB Suggested Anti-EIF4B Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateEIF4B is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
Image 2
Human Heart
Rabbit Anti-EIF4B Antibody
Catalog Number: ARP40359
Paraffin Embedded Tissue: Human Heart
Cellular Data: Myocardial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
 

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