Product Number |
ARP40278_P050 |
Product Page |
www.avivasysbio.com/fus-antibody-n-terminal-region-arp40278-p050.html |
Name |
FUS Antibody - N-terminal region (ARP40278_P050) |
Protein Size (# AA) |
526 amino acids |
Molecular Weight |
53 kDa |
NCBI Gene Id |
2521 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Fused in sarcoma |
Alias Symbols |
TLS, ALS6, ETM4, FUS1, POMP75, altFUS, HNRNPP2 |
Peptide Sequence |
Synthetic peptide located within the following region: MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Sato,S., (2005) Gastroenterology 129 (4), 1225-1236 |
Description of Target |
FUS binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS may play a role in maintenance of genomic integrity. |
Protein Interactions |
TBPL1; TRIP4; RPL14; HIST2H2BE; RAB7A; TUBA1A; DDX42; ATXN2L; CPSF6; NUDT21; YWHAQ; CKAP4; SF3A3; CCT8; PAICS; CCT2; CCT4; CCT7; SYNCRIP; TUBA1B; SF3A1; SF3B4; ABCF2; SAE1; SF1; YWHAZ; VCP; UBA1; UBC; TUFM; CCT3; HSP90B1; TP73; TKT; TCP1; TCEB1; STATH; ST |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
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Datasheets/Manuals |
Printable datasheet for anti-FUS (ARP40278_P050) antibody |
Blocking Peptide |
For anti-FUS (ARP40278_P050) antibody is Catalog # AAP40278 (Previous Catalog # AAPP22988) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FUS |
Uniprot ID |
P35637 |
Sample Type Confirmation |
FUS is strongly supported by BioGPS gene expression data to be expressed in HepG2 |
Protein Accession # |
NP_001010850 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001010850 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
FUS |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Pig, Rabbit |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 93% |
Image 1 | Human Breast
| Rabbit Anti-FUS Antibody Catalog Number: ARP40278 Paraffin Embedded Tissue: Human Breast Antibody Concentration: 5 ug/ml |
|
Image 2 | Human Intestine
| Rabbit Anti-FUS Antibody Catalog Number: ARP40278 Paraffin Embedded Tissue: Human Intestine Cellular Data: Epithelial cells of intestinal villas Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
|
Image 3 | Human Lung
| Rabbit Anti-FUS Antibody Catalog Number: ARP40278 Paraffin Embedded Tissue: Human alveolar cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
|
Image 4 | mouse brain
| WB Suggested Anti-FUS Antibody Positive Control: Lane 1: 5ug mouse brain cytoplasm Lane 2: 5ug mouse brain nucleus Primary Antibody Dilution : 1:1000 Secondary Antibody : Anti rabbit - IR-dye Secondry Antibody Dilution : 1:10,000 Submitted by: Anonymous |
|
Image 5 | Human MCF-7, THP-1, Hela cell lysates
| Host: Rabbit Target Name: FUS Sample Type: Lane 1: Human MCF-7 cell lysateK562 Lane 2: Human THP-1 cell lysate Lane 3: Human Hela cell lysate Antibody Dilution: 1.0ug/ml |
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