| Product Number |
ARP40276_T100 |
| Product Page |
www.avivasysbio.com/snrp70-antibody-n-terminal-region-arp40276-t100.html |
| Name |
SNRP70 Antibody - N-terminal region (ARP40276_T100) |
| Protein Size (# AA) |
437 amino acids |
| Molecular Weight |
52kDa |
| NCBI Gene Id |
6625 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Small nuclear ribonucleoprotein 70kDa (U1) |
| Alias Symbols |
RPU1, Snp1, U1AP, U170K, U1RNP, RNPU1Z, SNRP70, U1-70K |
| Peptide Sequence |
Synthetic peptide located within the following region: YLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERK |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Brandenberger,R., (2004) Nat. Biotechnol. 22 (6), 707-716 |
| Description of Target |
SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests. |
| Protein Interactions |
IL32; UBC; NEDD8; LIN28A; EZH2; SUZ12; EED; RNF2; rev; WBP4; SRPK2; SRPK1; MYC; SRPK3; HDAC2; PAN2; SMURF2; PRPF40A; CDKL3; RNF11; PRKD2; SKIL; RELA; RASGRF1; SMAD9; SMAD5; SMAD4; SMAD3; SMAD2; CHERP; PRMT5; UBL4A; VCAM1; SMAD1; ITGA4; IL7R; IFIT3; IFIT1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SNRNP70 (ARP40276_T100) antibody |
| Blocking Peptide |
For anti-SNRNP70 (ARP40276_T100) antibody is Catalog # AAP40276 (Previous Catalog # AAPP10313) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SNRP70 |
| Uniprot ID |
P08621 |
| Protein Name |
U1 small nuclear ribonucleoprotein 70 kDa |
| Sample Type Confirmation |
SNRNP70 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
NP_003080 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_003089 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SNRNP70 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | HEK293
 | WB Suggested Anti-SNRP70 antibody Titration: 1 ug/mL
Sample Type: HEK293 |
|
| Image 2 | Human Raji
 | WB Suggested Anti-SNRP70 antibody Titration: 1 ug/mL
Sample Type: Human Raji |
|
| Image 3 | Human HepG2
 | WB Suggested Anti-SNRP70 Antibody Titration: 5.0ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysateSNRNP70 is supported by BioGPS gene expression data to be expressed in HepG2 |
|
| Image 4 | Human Kidney
 | Rabbit Anti-SNRP70 Antibody
Catalog Number: ARP40276
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
