RBMS3 Antibody - N-terminal region (ARP40234_T100)

Data Sheet
 
Product Number ARP40234_T100
Product Page www.avivasysbio.com/rbms3-antibody-n-terminal-region-arp40234-t100.html
Name RBMS3 Antibody - N-terminal region (ARP40234_T100)
Protein Size (# AA) 419 amino acids
Molecular Weight 46kDa
NCBI Gene Id 27303
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name RNA binding motif, single stranded interacting protein 3
Peptide Sequence Synthetic peptide located within the following region: GVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDA
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Penkov,D., Gene 243 (1-2), 27-36 (2000)
Description of Target RBMS3 is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis.The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-RBMS3 (ARP40234_T100) antibody
Blocking Peptide For anti-RBMS3 (ARP40234_T100) antibody is Catalog # AAP40234 (Previous Catalog # AAPS02804)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human RBMS3
Uniprot ID Q6XE24-3
Protein Name RNA-binding motif, single-stranded-interacting protein 3
Protein Accession # NP_001003792
Purification Protein A purified
Nucleotide Accession # NM_001003792
Tested Species Reactivity Human
Gene Symbol RBMS3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Human HepG2
WB Suggested Anti-RBMS3 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate
 

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