| Product Number |
ARP40225_T100 |
| Product Page |
www.avivasysbio.com/exosc10-antibody-c-terminal-region-arp40225-t100.html |
| Name |
EXOSC10 Antibody - C-terminal region (ARP40225_T100) |
| Protein Size (# AA) |
885 amino acids |
| Molecular Weight |
97kDa |
| NCBI Gene Id |
5394 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Exosome component 10 |
| Alias Symbols |
p2, p3, p4, RRP6, PMSCL, Rrp6p, PM-Scl, PMSCL2, PM/Scl-100 |
| Peptide Sequence |
Synthetic peptide located within the following region: FAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lehner,B. (2004) Genome Res. 14 (7), 1315-1323 |
| Description of Target |
EXOSC10 contains 1 HRDC domain and 1 3'-5' exonuclease domain. Antibodies against PM/SCL are found in patients with polymyositis and/or scleroderma. |
| Protein Interactions |
SUMO2; UBC; SUMO1; RPA3; RPA2; RPA1; NOMO2; EXOSC6; FERMT3; CHPF; LSM2; EXOSC5; FOXRED1; EXOSC4; XRN1; LSM8; B9D1; USP21; UPF2; NOMO1; EXOSC7; DIS3; EXOSC8; IMMT; RUVBL2; EIF3M; TOX4; SSRP1; SKIV2L; LCAT; DXO; ALDH1B1; AICDA; ESR1; EXOSC3; EXOSC9; DIS3L; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-EXOSC10 (ARP40225_T100) antibody |
| Blocking Peptide |
For anti-EXOSC10 (ARP40225_T100) antibody is Catalog # AAP40225 (Previous Catalog # AAPP22069) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human EXOSC10 |
| Uniprot ID |
Q01780 |
| Protein Name |
Exosome component 10 |
| Sample Type Confirmation |
EXOSC10 is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_001001998 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001001998 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
EXOSC10 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 79%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-EXOSC10 Antibody Titration: 5.0ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateEXOSC10 is supported by BioGPS gene expression data to be expressed in Jurkat |
|
| Image 2 | Human Intestine
 | Rabbit Anti-EXOSC10 Antibody
Catalog Number: ARP40225
Paraffin Embedded Tissue: Human Intestine
Cellular Data: Epithelial cells of intestinal villas
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
