RPLP0 Antibody - middle region (ARP40222_T100)

Data Sheet
 
Product Number ARP40222_T100
Product Page www.avivasysbio.com/rplp0-antibody-middle-region-arp40222-t100.html
Name RPLP0 Antibody - middle region (ARP40222_T100)
Protein Size (# AA) 317 amino acids
Molecular Weight 35kDa
NCBI Gene Id 6175
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Ribosomal protein, large, P0
Alias Symbols P0, LP0, L10E, RPP0, PRLP0
Peptide Sequence Synthetic peptide located within the following region: PFSFGLVIQQVFDNGSIYNPEVLDITEETLHSRFLEGVRNVASVCLQIGY
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Brendel,C., Biochem. J. 384 (PT 2), 239-246 (2004)
Description of Target Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. The ribosomal protein is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Protein Interactions HUWE1; CCNDBP1; UBC; TP53; HAUS2; CEP250; TUBG1; AURKA; SUMO2; SUMO3; STAU1; RPA3; RPA2; RPA1; ERG; ZBTB1; PRPF40A; RPL36; FARSB; EEF1E1; AIMP1; LRRFIP1; IQGAP1; GAS7; RPLP1; RPL24; RPL23A; RPL21; RPL19; RPL18; RPL15; RPL13; RPL7A; MARS; IARS; DNAJA1; FAR
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-RPLP0 (ARP40222_T100) antibody
Blocking Peptide For anti-RPLP0 (ARP40222_T100) antibody is Catalog # AAP40222 (Previous Catalog # AAPP23490)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human RPLP0
Uniprot ID P05388
Protein Name 60S acidic ribosomal protein P0
Sample Type Confirmation

RPLP0 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_000993
Purification Protein A purified
Nucleotide Accession # NM_001002
Tested Species Reactivity Human
Gene Symbol RPLP0
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%; Zebrafish: 79%
Image 1
Human Hela
Host: Rabbit
Target Name: RPLP0
Sample Tissue: Human Hela
Antibody Dilution: 1.0ug/ml
 

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