Product Number |
ARP40222_T100 |
Product Page |
www.avivasysbio.com/rplp0-antibody-middle-region-arp40222-t100.html |
Name |
RPLP0 Antibody - middle region (ARP40222_T100) |
Protein Size (# AA) |
317 amino acids |
Molecular Weight |
35kDa |
NCBI Gene Id |
6175 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Ribosomal protein, large, P0 |
Alias Symbols |
P0, LP0, L10E, RPP0, PRLP0 |
Peptide Sequence |
Synthetic peptide located within the following region: PFSFGLVIQQVFDNGSIYNPEVLDITEETLHSRFLEGVRNVASVCLQIGY |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Brendel,C., Biochem. J. 384 (PT 2), 239-246 (2004) |
Description of Target |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. The ribosomal protein is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. |
Protein Interactions |
HUWE1; CCNDBP1; UBC; TP53; HAUS2; CEP250; TUBG1; AURKA; SUMO2; SUMO3; STAU1; RPA3; RPA2; RPA1; ERG; ZBTB1; PRPF40A; RPL36; FARSB; EEF1E1; AIMP1; LRRFIP1; IQGAP1; GAS7; RPLP1; RPL24; RPL23A; RPL21; RPL19; RPL18; RPL15; RPL13; RPL7A; MARS; IARS; DNAJA1; FAR |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-RPLP0 (ARP40222_T100) antibody |
Blocking Peptide |
For anti-RPLP0 (ARP40222_T100) antibody is Catalog # AAP40222 (Previous Catalog # AAPP23490) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human RPLP0 |
Uniprot ID |
P05388 |
Protein Name |
60S acidic ribosomal protein P0 |
Sample Type Confirmation |
RPLP0 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_000993 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001002 |
Tested Species Reactivity |
Human |
Gene Symbol |
RPLP0 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%; Zebrafish: 79% |
Image 1 | Human Hela
| Host: Rabbit Target Name: RPLP0 Sample Tissue: Human Hela Antibody Dilution: 1.0ug/ml |
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