Product Number |
ARP40206_T100 |
Product Page |
www.avivasysbio.com/krt18-antibody-c-terminal-region-arp40206-t100.html |
Name |
KRT18 Antibody - C-terminal region (ARP40206_T100) |
Protein Size (# AA) |
430 amino acids |
Molecular Weight |
47kDa |
NCBI Gene Id |
3875 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Keratin 18 |
Alias Symbols |
K18, CK-18, CYK18 |
Peptide Sequence |
Synthetic peptide located within the following region: ALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIV |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Ku,N.O., (2005) Gastroenterology 129 (3), 885-893 |
Description of Target |
KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. |
Protein Interactions |
KRT18; GOLGA2; UBC; HAUS1; CCDC146; MDM2; EED; HNRNPU; FLII; FKBP3; DDX1; C14orf166; RTCB; CNOT1; SEC16A; RPL14; RFC2; UPF2; BBS7; PAN2; BBS4; BBS2; BBS1; SMARCD1; ORC5; NOS2; KRT8; KPNA2; ITGA4; HRAS; GRN; FN1; EP300; ATF2; CDH1; CDC5L; YTHDC1; PIAS4; TX |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-KRT18 (ARP40206_T100) antibody |
Blocking Peptide |
For anti-KRT18 (ARP40206_T100) antibody is Catalog # AAP40206 (Previous Catalog # AAPP22050) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human KRT18 |
Uniprot ID |
P05783 |
Protein Name |
Keratin, type I cytoskeletal 18 |
Sample Type Confirmation |
KRT18 is supported by BioGPS gene expression data to be expressed in HepG2 |
Protein Accession # |
NP_000215 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_000224 |
Tested Species Reactivity |
Human |
Gene Symbol |
KRT18 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 77%; Rat: 100%; Zebrafish: 83% |
Image 1 | Human Lung
| Rabbit Anti-KRT18 Antibody Catalog Number: ARP40206 Paraffin Embedded Tissue: Human Lung Cellular Data: Alveolar cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
|
Image 2 | Human HepG2
| WB Suggested Anti-KRT18 Antibody Titration: 1.25ug/ml ELISA Titer: 1:62500 Positive Control: HepG2 cell lysateKRT18 is supported by BioGPS gene expression data to be expressed in HepG2 |
|
Image 3 | Human HepG2
| WB Suggested Anti-KRT18 antibody Titration: 1 ug/mL Sample Type: Human HepG2 |
|
Image 4 | Human Hela
| WB Suggested Anti-KRT18 antibody Titration: 1 ug/mL Sample Type: Human Hela |
|