Product Number |
ARP40204_T100 |
Product Page |
www.avivasysbio.com/anp32a-antibody-n-terminal-region-arp40204-t100.html |
Name |
ANP32A Antibody - N-terminal region (ARP40204_T100) |
Protein Size (# AA) |
249 amino acids |
Molecular Weight |
29kDa |
NCBI Gene Id |
8125 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
Description |
|
Alias Symbols |
LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1 |
Peptide Sequence |
Synthetic peptide located within the following region: MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTI |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Stelzl,U., (2005) Cell 122 (6), 957-968 |
Description of Target |
ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity. |
Protein Interactions |
UBC; rev; PDLIM5; PLIN3; ARPC1B; OXSR1; EIF4A3; VBP1; TPD52L2; SSB; SRP14; RPA2; PKM; BAG1; SOX2; PCBP1; ESR1; THRB; PPARG; PGR; KPNA6; KPNA5; KPNA1; SUMO2; CHAF1A; HIST1H4A; HIST1H3A; HIST2H2BE; HIST2H2AC; SET; MEPCE; ELAVL1; ADAP1; NSFL1C; HSPB3; AXIN1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ANP32A (ARP40204_T100) antibody |
Blocking Peptide |
For anti-ANP32A (ARP40204_T100) antibody is Catalog # AAP40204 (Previous Catalog # AAPS01610) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ANP32A |
Uniprot ID |
P39687 |
Protein Name |
Acidic leucine-rich nuclear phosphoprotein 32 family member A |
Sample Type Confirmation |
ANP32A is supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_006296 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_006305 |
Tested Species Reactivity |
Human |
Gene Symbol |
ANP32A |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 93%; Rat: 86%; Sheep: 77%; Zebrafish: 93% |
Image 1 | Human Jurkat
| WB Suggested Anti-ANP32A Antibody Titration: 1.25ug/ml Positive Control: Jurkat cell lysateANP32A is supported by BioGPS gene expression data to be expressed in Jurkat |
|
Image 2 | Human Heart
| Rabbit Anti-ANP32A Antibody Catalog Number: ARP40204 Paraffin Embedded Tissue: Human Heart Cellular Data: Myocardial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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