ANP32A Antibody - N-terminal region (ARP40204_T100)

Data Sheet
 
Product Number ARP40204_T100
Product Page www.avivasysbio.com/anp32a-antibody-n-terminal-region-arp40204-t100.html
Name ANP32A Antibody - N-terminal region (ARP40204_T100)
Protein Size (# AA) 249 amino acids
Molecular Weight 29kDa
NCBI Gene Id 8125
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
Description
Alias Symbols LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1
Peptide Sequence Synthetic peptide located within the following region: MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTI
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Stelzl,U., (2005) Cell 122 (6), 957-968
Description of Target ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.
Protein Interactions UBC; rev; PDLIM5; PLIN3; ARPC1B; OXSR1; EIF4A3; VBP1; TPD52L2; SSB; SRP14; RPA2; PKM; BAG1; SOX2; PCBP1; ESR1; THRB; PPARG; PGR; KPNA6; KPNA5; KPNA1; SUMO2; CHAF1A; HIST1H4A; HIST1H3A; HIST2H2BE; HIST2H2AC; SET; MEPCE; ELAVL1; ADAP1; NSFL1C; HSPB3; AXIN1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ANP32A (ARP40204_T100) antibody
Blocking Peptide For anti-ANP32A (ARP40204_T100) antibody is Catalog # AAP40204 (Previous Catalog # AAPS01610)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ANP32A
Uniprot ID P39687
Protein Name Acidic leucine-rich nuclear phosphoprotein 32 family member A
Sample Type Confirmation

ANP32A is supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_006296
Purification Protein A purified
Nucleotide Accession # NM_006305
Tested Species Reactivity Human
Gene Symbol ANP32A
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 93%; Rat: 86%; Sheep: 77%; Zebrafish: 93%
Image 1
Human Jurkat
WB Suggested Anti-ANP32A Antibody Titration: 1.25ug/ml
Positive Control: Jurkat cell lysateANP32A is supported by BioGPS gene expression data to be expressed in Jurkat
Image 2
Human Heart
Rabbit Anti-ANP32A Antibody
Catalog Number: ARP40204
Paraffin Embedded Tissue: Human Heart
Cellular Data: Myocardial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
 

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