| Product Number |
ARP40203_P050 |
| Product Page |
www.avivasysbio.com/anp32a-antibody-middle-region-arp40203-p050.html |
| Name |
ANP32A Antibody - middle region (ARP40203_P050) |
| Protein Size (# AA) |
249 amino acids |
| Molecular Weight |
29kDa |
| NCBI Gene Id |
8125 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| Alias Symbols |
LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1 |
| Peptide Sequence |
Synthetic peptide located within the following region: FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Stelzl,U., (2005) Cell 122 (6), 957-968 |
| Description of Target |
ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity. |
| Protein Interactions |
UBC; rev; PDLIM5; PLIN3; ARPC1B; OXSR1; EIF4A3; VBP1; TPD52L2; SSB; SRP14; RPA2; PKM; BAG1; SOX2; PCBP1; ESR1; THRB; PPARG; PGR; KPNA6; KPNA5; KPNA1; SUMO2; CHAF1A; HIST1H4A; HIST1H3A; HIST2H2BE; HIST2H2AC; SET; MEPCE; ELAVL1; ADAP1; NSFL1C; HSPB3; AXIN1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ANP32A (ARP40203_P050) antibody |
| Blocking Peptide |
For anti-ANP32A (ARP40203_P050) antibody is Catalog # AAP40203 (Previous Catalog # AAPS01612) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human ANP32A |
| Uniprot ID |
P39687 |
| Protein Name |
Acidic leucine-rich nuclear phosphoprotein 32 family member A |
| Sample Type Confirmation |
ANP32A is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_006296 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006305 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
ANP32A |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Sheep: 86%; Zebrafish: 86% |
| Image 1 | human kidney
 | Rabbit Anti-ANP32A Antibody
Catalog Number: ARP40203
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 2 | Mouse cortex brain
 | Lanes:
Lane1: 10ug mouse cortex brain lysate
Lane2: 25ug mouse cortex brain lysate
Lane3: 40ug mouse cortex brain lysate
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Anti-rabbit HRP
Secondary Antibody Dilution:
1:2000
Gene Name:
ANP32A
Submitted by:
Anonymous
|
|
| Image 3 | Human Jurkat
 | WB Suggested Anti-ANP32A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysateANP32A is supported by BioGPS gene expression data to be expressed in Jurkat |
|
| Image 4 | Human Heart
 | Rabbit Anti-ANP32A antibody
Catalog Number: ARP40203
Paraffin Embedded Tissue: Human Heart cell Cellular Data: cardiac cell of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
