HMBOX1 Antibody - N-terminal region (ARP39599_T100)

Data Sheet
 
Product Number ARP39599_T100
Product Page www.avivasysbio.com/hmbox1-antibody-n-terminal-region-arp39599-t100.html
Name HMBOX1 Antibody - N-terminal region (ARP39599_T100)
Protein Size (# AA) 420 amino acids
Molecular Weight 47kDa
NCBI Gene Id 79618
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Homeobox containing 1
Alias Symbols HOT1, TAH1, PBHNF, HNF1LA
Peptide Sequence Synthetic peptide located within the following region: ETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDK
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Strausberg,R.L., (2002) Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903
Description of Target HMBOX1 is located at the boundary of 8p12.3 and 8p21.1. HMBOX1 proteins are highly conserved in human, mouse, rat, chicken and Xenopus laevis. Functional HMBOX1::EGFP (enhanced green fluorescent protein) fusion protein revealed that HMBOX1 accumulated more in cytoplasm than in nucleus. HMBOX1 is a transcription repressor. Human HMBOX1 is widely expressed in 18 tissues, and it is highly expressed in pancreas. Hmbox1 is widely expressed in mouse pancreas and the expression of this gene can also be detected in pallium, hippocampus and hypothalamus.
Protein Interactions FAM74A4; PKD1P1; FAM13C; TCEANC; RBMY2FP; ZMAT2; ZNF417; DYNLL2; ASB7; FRMD6; AEBP2; SFR1; REEP6; ZNF587; LNX1; FAM161A; SAP30L; HMBOX1; C20orf195; C8orf33; UBE2Z; MRPL11; CARD9; SH2D4A; CBX8; UBA6; FAM206A; ZNF581; MAGEH1; ZNF337; MORF4L1; FARS2; MRPL28;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-HMBOX1 (ARP39599_T100) antibody
Blocking Peptide For anti-HMBOX1 (ARP39599_T100) antibody is Catalog # AAP39599 (Previous Catalog # AAPP21619)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human HMBOX1
Uniprot ID Q6NT76
Protein Name Homeobox-containing protein 1
Protein Accession # NP_078843
Purification Protein A purified
Nucleotide Accession # NM_024567
Tested Species Reactivity Human, Mouse
Gene Symbol HMBOX1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Image 1
Human Jurkat
WB Suggested Anti-HMBOX1 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate
Image 2
Mouse Brain
Host: Mouse
Target Name: HMBOX1
Sample Tissue: Mouse Brain
Antibody Dilution: 1ug/ml
 

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