FOXA2 Antibody - C-terminal region (ARP39509_T100)

Data Sheet
 
Product Number ARP39509_T100
Product Page www.avivasysbio.com/foxa2-antibody-c-terminal-region-arp39509-t100.html
Name FOXA2 Antibody - C-terminal region (ARP39509_T100)
Protein Size (# AA) 457 amino acids
Molecular Weight 48kDa
NCBI Gene Id 3170
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Forkhead box A2
Alias Symbols HNF3B, TCF3B, HNF-3-beta
Peptide Sequence Synthetic peptide located within the following region: QVMHYPGYGSPMPGSLAMGPVTNKTGLDASPLAADTSYYQGVYSRPIMNS
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Verschuur,M., (2005) J. Biol. Chem. 280 (17), 16763-16771
Description of Target FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.
Protein Interactions PPARGC1B; GSC; EN2; OTX2; ONECUT1; NCOA1; TLE1; MIP; HOXA5; LHX1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-FOXA2 (ARP39509_T100) antibody
Blocking Peptide For anti-FOXA2 (ARP39509_T100) antibody is Catalog # AAP39509 (Previous Catalog # AAPP21525)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human FOXA2
Uniprot ID Q9Y261
Protein Name Hepatocyte nuclear factor 3-beta
Sample Type Confirmation

FOXA2 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Protein Accession # NP_068556
Purification Protein A purified
Nucleotide Accession # NM_021784
Tested Species Reactivity Human
Gene Symbol FOXA2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 86%; Rat: 93%
Image 1
Human HepG2
WB Suggested Anti-FOXA2 Antibody Titration: 0.625ug/ml
ELISA Titer: 1:12500
Positive Control: HepG2 cell lysateFOXA2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells
 

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