Product Number |
ARP39467_P050 |
Product Page |
www.avivasysbio.com/deaf1-antibody-n-terminal-region-arp39467-p050.html |
Name |
DEAF1 Antibody - N-terminal region (ARP39467_P050) |
Protein Size (# AA) |
565 amino acids |
Molecular Weight |
59kDa |
NCBI Gene Id |
10522 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Deformed epidermal autoregulatory factor 1 (Drosophila) |
Alias Symbols |
SPN, NUDR, VSVS, MRD24, ZMYND5, NEDHELS |
Peptide Sequence |
Synthetic peptide located within the following region: EEPVLSRDEDSEEDADSEAERETPRVTAVAVMAAEPGHMDMGAEALPGPD |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Czesak,M., (2006) J. Neurosci. 26 (6), 1864-1871 |
Description of Target |
DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. |
Protein Interactions |
IRF7; IRF3; CREB1; PELI1; PELI2; HRSP12; GSK3B; GSK3A; CDKN2A; PPP1CC; PPP1CA; CDC37; AIMP2; TK1; RAD23B; PIN1; HRAS; FHL1; CDKN1A; ASCC2; INTS1; LMO4; DEAF1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-DEAF1 (ARP39467_P050) antibody |
Blocking Peptide |
For anti-DEAF1 (ARP39467_P050) antibody is Catalog # AAP39467 (Previous Catalog # AAPP21481) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human DEAF1 |
Uniprot ID |
O75398 |
Protein Name |
Deformed epidermal autoregulatory factor 1 homolog |
Protein Accession # |
NP_066288 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_021008 |
Tested Species Reactivity |
Human |
Gene Symbol |
DEAF1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Yeast |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 83%; Dog: 93%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 100% |
Image 1 | Hum. Fetal Lung
| Hum. Fetal Lung |
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Image 2 | Hum. Fetal Muscle
| Hum. Fetal Muscle |
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Image 3 | Hum. Adult Placenta
| Hum. Adult Placenta |
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Image 4 | Human Brain
| WB Suggested Anti-DEAF1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Human brain |
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