ERGIC2 Antibody - N-terminal region (ARP39265_T100)

Data Sheet
 
Product Number ARP39265_T100
Product Page www.avivasysbio.com/ergic2-antibody-n-terminal-region-arp39265-t100.html
Name ERGIC2 Antibody - N-terminal region (ARP39265_T100)
Protein Size (# AA) 377 amino acids
Molecular Weight 43kDa
NCBI Gene Id 51290
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name ERGIC and golgi 2
Alias Symbols PTX1, CDA14, Erv41, cd002
Peptide Sequence Synthetic peptide located within the following region: MRRLNRKKTLSLVKELDAFPKVPESYVETSASGGTVSLIAFTTMALLTIM
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Breuza,L., (2004) J. Biol. Chem. 279 (45), 47242-47253
Description of Target ERGIon Channel2 possibly play role in transport between endoplasmic reticulum and Golgi. ERGIon Channel2 is downregulated in prostate cancer. ERGIon Channel2 may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells. Ectopic expression of a partial sequence of ERGIon Channel2 as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. Interferon-beta (IFN-beta) and a number of IFN-inducible genes were upregulated by the ERGIon Channel2-VP22 fusion protein.
Protein Interactions env; UBC; Copa;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ERGIC2 (ARP39265_T100) antibody
Blocking Peptide For anti-ERGIC2 (ARP39265_T100) antibody is Catalog # AAP39265 (Previous Catalog # AAPY00875)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ERGIC2
Uniprot ID Q96RQ1
Protein Name Endoplasmic reticulum-Golgi intermediate compartment protein 2
Protein Accession # NP_057654
Purification Protein A purified
Nucleotide Accession # NM_016570
Tested Species Reactivity Human
Gene Symbol ERGIC2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 93%; Guinea Pig: 87%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 93%
Image 1
Human HepG2
WB Suggested Anti-ERGIC2 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
 

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