Product Number |
ARP39254_T100 |
Product Page |
www.avivasysbio.com/gtf2ird1-antibody-c-terminal-region-arp39254-t100.html |
Name |
GTF2IRD1 Antibody - C-terminal region (ARP39254_T100) |
Protein Size (# AA) |
959 amino acids |
Molecular Weight |
106kDa |
NCBI Gene Id |
9569 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
GTF2I repeat domain containing 1 |
Alias Symbols |
BEN, WBS, GTF3, RBAP2, CREAM1, MUSTRD1, WBSCR11, WBSCR12, hMusTRD1alpha1 |
Peptide Sequence |
Synthetic peptide located within the following region: VIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSS |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Tassabehji,M., (2005) Science 310 (5751), 1184-1187 |
Description of Target |
GTF2IRD1 contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. GTF2IRD1 is related to Williams-Beuren syndrome, a multisystem developmental disorder. Western blots using three different antibodies against three unique regions of this protein target confirm the same apparent molecular weight in our tests. The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants. |
Protein Interactions |
UBC; SUMO2; USF1; HDAC3; SMAD2; EXOSC4; CDK20; PIAS2; SMAD3; NFI1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-GTF2IRD1 (ARP39254_T100) antibody |
Blocking Peptide |
For anti-GTF2IRD1 (ARP39254_T100) antibody is Catalog # AAP39254 (Previous Catalog # AAPY00864) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2IRD1 |
Uniprot ID |
Q9UHL9 |
Protein Name |
General transcription factor II-I repeat domain-containing protein 1 |
Protein Accession # |
NP_057412 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_016328 |
Tested Species Reactivity |
Human |
Gene Symbol |
GTF2IRD1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Yeast |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79% |
Image 1 | Human kidney
| Human kidney |
|
Image 2 | Transfected 293T
| WB Suggested Anti-GTF2IRD1 Antibody Titration: 2.5ug/ml ELISA Titer: 1:312500 Positive Control: Transfected 293T |
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