Product Number |
ARP39018_P050 |
Product Page |
www.avivasysbio.com/brd7-antibody-c-terminal-region-arp39018-p050.html |
Name |
BRD7 Antibody - C-terminal region (ARP39018_P050) |
Protein Size (# AA) |
651 amino acids |
Molecular Weight |
74kDa |
NCBI Gene Id |
29117 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Bromodomain containing 7 |
Alias Symbols |
BP75, NAG4, CELTIX1 |
Peptide Sequence |
Synthetic peptide located within the following region: KELAQQVTPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDV |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Zhou,J., (2004) J. Cell. Physiol. 200 (1), 89-98 |
Description of Target |
BRD7 is an activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. It induces dephosphorylation of GSK3B at 'Tyr-216'. |
Protein Interactions |
UBC; Dvl1; HIST2H3C; BRD2; NEFL; BARD1; LRIF1; HAP1; TFAP4; TRIM24; SUMO2; SMARCE1; SMARCD1; SMARCC2; Bcl7b; CHD7; ARID2; RBFOX2; BCL7C; SMARCC1; SMARCA4; PCBD1; POU2F1; MYC; BRCA1; BHLHE40; HIST2H4A; HIST2H3A; BTBD2; RIF1; HNRNPUL1; HIST1H2AL; AGR2; PSMD |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-BRD7 (ARP39018_P050) antibody |
Blocking Peptide |
For anti-BRD7 (ARP39018_P050) antibody is Catalog # AAP39018 (Previous Catalog # AAPS03711) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human BRD7 |
Uniprot ID |
Q9NPI1 |
Protein Name |
Bromodomain-containing protein 7 |
Sample Type Confirmation |
BRD7 is supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_037395 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_013263 |
Tested Species Reactivity |
Human |
Gene Symbol |
BRD7 |
Predicted Species Reactivity |
Human, Rat, Dog, Guinea Pig, Horse, Rabbit |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Dog: 86%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Rabbit: 79%; Rat: 86% |
Image 1 | Human Jurkat
| WB Suggested Anti-BRD7 Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat cell lysateBRD7 is supported by BioGPS gene expression data to be expressed in Jurkat |
|
Image 2 | Jurkat
| Host: Rabbit Target Name: BRD7 Sample Type: Jurkat Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 2.5ug/mL Peptide Concentration: 2.0ug/mL Lysate Quantity: 25ug/lane Gel Concentration: 12%BRD7 is supported by BioGPS gene expression data to be expressed in Jurkat |
|
Image 3 | Human Lung
| Rabbit Anti-BRD7 antibody
Catalog Number: ARP39018
Paraffin Embedded Tissue: Human Lung
cell Cellular Data: alveolar cell
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
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