| Product Number |
ARP38984_T100 |
| Product Page |
www.avivasysbio.com/maff-antibody-n-terminal-region-arp38984-t100.html |
| Name |
MAFF Antibody - N-terminal region (ARP38984_T100) |
| Protein Size (# AA) |
164 amino acids |
| Molecular Weight |
18kDa |
| NCBI Gene Id |
23764 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
V-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) |
| Alias Symbols |
U-MAF, hMafF |
| Peptide Sequence |
Synthetic peptide located within the following region: SVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Marini,M.G., (2002) Blood Cells Mol. Dis. 29 (2), 145-158 |
| Description of Target |
MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene. |
| Protein Interactions |
NFE2L2; PARP1; BACH2; BATF3; MAFF; NFE2L3; NFIL3; NFE2L1; MAFG; FOS; DDIT3; BACH1; ATF3; BATF2; MAFIP; OVOL1; SUMO2; GTF2A1L; HDAC5; PPARG; NR3C1; NFE2; NRF1; PSAP; PRRX1; HOXD12; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MAFF (ARP38984_T100) antibody |
| Blocking Peptide |
For anti-MAFF (ARP38984_T100) antibody is Catalog # AAP38984 (Previous Catalog # AAPY00791) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human MAFF |
| Uniprot ID |
Q9ULX9 |
| Protein Name |
Transcription factor MafF |
| Protein Accession # |
NP_690617 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_152878 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MAFF |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-MAFF Antibody Titration: 5.0ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate |
|
