ILF3 Antibody - C-terminal region (ARP38969_T100)

Data Sheet
 
Product Number ARP38969_T100
Product Page www.avivasysbio.com/ilf3-antibody-c-terminal-region-arp38969-t100.html
Name ILF3 Antibody - C-terminal region (ARP38969_T100)
Protein Size (# AA) 894 amino acids
Molecular Weight 95kDa
NCBI Gene Id 3609
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Interleukin enhancer binding factor 3, 90kDa
Alias Symbols CBTF, DRBF, MMP4, MPP4, NF90, NFAR, NF110, NF90a, NF90b, NF90c, NFAR2, TCP80, DRBP76, NF110b, NFAR-1, NFAR-2, NFAR90, TCP110, MPP4110, NF90ctv, NFAR110, MPHOSPH4, NF-AT-90
Peptide Sequence Synthetic peptide located within the following region: SYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Nie,Y., (2005) Mol. Cell. Biol. 25 (16), 6956-6963
Description of Target ILF3 may facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. ILF3 can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. ILF3 can regulate protein arginine N-methyltransferase 1 activity. ILF3 may regulate transcription of the IL2 gene during T-cell activation. It can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.
Protein Interactions PLSCR1; UBC; FBXW11; RBPMS; HUWE1; MDM2; AURKA; SUMO2; SUMO3; STAU1; IVNS1ABP; LGR4; ERG; RPA3; RPA2; RPA1; EZH2; HNRNPL; SUZ12; RNF2; BMI1; EED; VHL; VEGFA; rev; FBXO6; TARDBP; CSF2; EIF2AK2; ICAM1; IGSF8; SNORD116-22; PABPC1; RNU2-4P; RNU5B-1; RNU5A-1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ILF3 (ARP38969_T100) antibody
Blocking Peptide For anti-ILF3 (ARP38969_T100) antibody is Catalog # AAP38969 (Previous Catalog # AAPY00777)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human ILF3
Uniprot ID Q12906
Protein Name Interleukin enhancer-binding factor 3
Sample Type Confirmation

ILF3 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Protein Accession # NP_036350
Purification Protein A purified
Nucleotide Accession # NM_012218
Tested Species Reactivity Human
Gene Symbol ILF3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 86%
Image 1
Human HepG2
WB Suggested Anti-ILF3 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysateILF3 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells
 

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