CORO1A Antibody - C-terminal region (ARP38900_T100)

Data Sheet
 
Product Number ARP38900_T100
Product Page www.avivasysbio.com/coro1a-antibody-c-terminal-region-arp38900-t100.html
Name CORO1A Antibody - C-terminal region (ARP38900_T100)
Protein Size (# AA) 461 amino acids
Molecular Weight 51kDa
NCBI Gene Id 11151
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Coronin, actin binding protein, 1A
Alias Symbols p57, IMD8, TACO, CLABP, HCORO1, CLIPINA
Peptide Sequence Synthetic peptide located within the following region: ELRVNRGLDTGRRRAAPEASGTPSSDAVSRLEEEMRKLQATVQELQKRLD
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Anand,P.K. (2005) FEMS Microbiol. Lett. 250 (1), 137-144
Description of Target CORO1A is a novel actin-binding protein with a WD repeat and a leucine zipper motif. CORO1A forms homodimers, that the association is mediated by the leucine zipper structure in the C-terminal region, and that it plays a role in the cross-linking of F-actin in the cell. The leukocyte plasma membrane associates with the actin cytoskeleton through CORO1A.Downregulation of CORO1A gene transcription restricts entry/survival of mycobacteria within macrophages
Protein Interactions FSD2; GOLGA2; UBC; YTHDC1; SPATA20; POT1; TAB1; GIT2; POLR1C; STAT3; SMARCD1; MAGOH; SMAD3; LMO2; FHL3; FMNL1; NCF4; THBS1; ACTB; DKK1; UBE2G2;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CORO1A (ARP38900_T100) antibody
Blocking Peptide For anti-CORO1A (ARP38900_T100) antibody is Catalog # AAP38900 (Previous Catalog # AAPY00709)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human CORO1A
Uniprot ID Q2YD73
Protein Name Coronin-1A
Sample Type Confirmation

CORO1A is supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_009005
Purification Protein A purified
Nucleotide Accession # NM_007074
Tested Species Reactivity Human
Gene Symbol CORO1A
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 77%; Pig: 90%; Rabbit: 79%; Rat: 83%
Image 1
Human Jurkat
WB Suggested Anti-CORO1A Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateCORO1A is supported by BioGPS gene expression data to be expressed in Jurkat
 

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