RXRG Antibody - C-terminal region (ARP38881_T100)

• Product Number: ARP38881_T100
• Name: RXRG Antibody - C-terminal region (ARP38881_T100)
• Protein Size (# AA): 463 amino acids
• Molecular Weight: 51kDa
• NCBI Gene Id: 6258
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Gene Full Name: Retinoid X receptor, gamma
• Alias Symbols: RXRC, NR2B3
• Peptide Sequence: Synthetic peptide located within the following region: LEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Bungard,C.I. Arch. Biochem. Biophys. 443 (1-2), 53-59 (2005)
• Description of Target: RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Protein Interactions: NR1H3; NR1H2; RARB; RARA; MPPED2; UBC; CUL1; DCK; NR1H4; NCOR2; NR1I2; VDR; THRB; RARG; PPARD; MAP4; CAMK2B; CEBPZ; HOXD4; AJUBA; RPAP2; LRSAM1; PNO1; CHGB; THRA; NCOA6; PPARG; SRF; CREBBP; PPARA; NR4A1; Nr0b2; ITGB3BP;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-RXRG (ARP38881_T100) antibody is Catalog # AAP38881 (Previous Catalog # AAPP21087)
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RXRG
• Uniprot ID: P48443
• Protein Name: Retinoic acid receptor RXR-gamma
• Protein Accession #: NP_008848
• Purification: Protein A purified
• Nucleotide Accession #: NM_006917
• Tested Species Reactivity: Human, Mouse
• Gene Symbol: RXRG
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
• Image 1: Mouse Spleen
  
  Host: Mouse
  Target Name: RXRG
  Sample Tissue: Mouse Spleen
  Antibody Dilution: 1ug/ml
• Image 2: Human Jurkat
  
  WB Suggested Anti-RXRG Antibody Titration: 2.5ug/ml
  Positive Control: Jurkat cell lysate