PDLIM5 Antibody - C-terminal region (ARP38796_T100)

• Product Number: ARP38796_T100
• Name: PDLIM5 Antibody - C-terminal region (ARP38796_T100)
• Protein Size (# AA): 596 amino acids
• Molecular Weight: 64kDa
• NCBI Gene Id: 10611
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Gene Full Name: PDZ and LIM domain 5
• Alias Symbols: L9, ENH, LIM, ENH1
• Peptide Sequence: Synthetic peptide located within the following region: AGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Lasorella,A. (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (13), 4976-4981
• Description of Target: PDLIM5 is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.
• Protein Interactions: KRTAP10-7; KRT40; CCDC136; COIL; ZYX; UBC; SUMO2; SUMO3; SUZ12; RNF2; BMI1; PDE12; NPLOC4; IPO11; PLIN3; UBA2; EIF4A3; ANP32A; TPD52; SRP14; RAD23B; PKM; METTL1; CBS; CALU; FN1; ELMSAN1; SIN3A; DSTN; NDUFA7; GFI1B; SUMO1; TRIM39; CACNA1B; PRKCG; PRKCE; PR
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-PDLIM5 (ARP38796_T100) antibody is Catalog # AAP38796 (Previous Catalog # AAPP21005)
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PDLIM5
• Uniprot ID: Q5UW38
• Protein Name: PDZ and LIM domain protein 5
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that PDLIM5 is expressed in HepG2

• Protein Accession #: NP_006448
• Purification: Protein A purified
• Nucleotide Accession #: NM_006457
• Tested Species Reactivity: Human
• Gene Symbol: PDLIM5
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
• Image 1: Human HepG2
  
  WB Suggested Anti-PDLIM5 Antibody Titration: 2.5ug/ml
  ELISA Titer: 1:1562500
  Positive Control: HepG2 cell lysateThere is BioGPS gene expression data showing that PDLIM5 is expressed in HepG2