| Product Number |
ARP38745_T100 |
| Product Page |
www.avivasysbio.com/nfe2l2-antibody-c-terminal-region-arp38745-t100.html |
| Name |
NFE2L2 Antibody - C-terminal region (ARP38745_T100) |
| Protein Size (# AA) |
605 amino acids |
| Molecular Weight |
68kDa |
| NCBI Gene Id |
4780 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Nuclear factor (erythroid-derived 2)-like 2 |
| Alias Symbols |
NRF2, HEBP1, Nrf-2, IMDDHH |
| Peptide Sequence |
Synthetic peptide located within the following region: KEKGENDKSLHLLKKQLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGN |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Padmanabhan,B., et al., (2006) Mol. Cell 21 (5), 689-700 |
| Description of Target |
NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other. NFE2L2 may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995).[supplied by OMIM]. |
| Protein Interactions |
BACH1; HDAC3; WAC; FBXW11; KEAP1; TNNT1; MAPK7; HDAC2; HDAC1; MAFF; MAFG; MAFK; MAP2K2; MAP2K1; MAPK9; MAPK8; AKT1; UBC; NQO1; BRCA1; AHR; CREB3; NFE2L3; ENC1; SIAH2; NFE2; ATF4; Pparg; SUMO1; SUMO2; RNF4; BPTF; RBMX; KPNA3; SUMO3; MYC; DYT10; Ube2e1; PGA |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NFE2L2 (ARP38745_T100) antibody |
| Blocking Peptide |
For anti-NFE2L2 (ARP38745_T100) antibody is Catalog # AAP38745 (Previous Catalog # AAPP20951) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human NFE2L2 |
| Uniprot ID |
Q16236 |
| Protein Name |
Nuclear factor erythroid 2-related factor 2 |
| Sample Type Confirmation |
NFE2L2 is supported by BioGPS gene expression data to be expressed in A172 |
| Protein Accession # |
NP_006155 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_006164 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NFE2L2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100% |
| Image 1 | Human A172
 | WB Suggested Anti-NFE2L2 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: A172 cell lysateNFE2L2 is supported by BioGPS gene expression data to be expressed in A172 |
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